135 Results for "

steroid hormone

" in MedChemExpress (MCE) Product Catalog:
Products (135)

135 Results for "steroid hormone" in MCE Product Catalog:

136
136 Publications Verification
Cat. No.: HY-B0141
CAS No.: 50-28-2
Synonyms: β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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136
136 Publications Verification
Cat. No.: HY-B0141C
CAS No.: 35380-71-3
Synonyms: β-Estradiol hemihydrate; 17β-Estradiol hemihydrate; 17β-Oestradiol hemihydrate
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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89
89 Cited Publications
Cat. No.: HY-N0583
CAS No.: 50-23-7
Synonyms: Cortisol
Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex .
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59
59 Cited Publications
Cat. No.: HY-14650
CAS No.: 53-43-0
Purity:  99.93%
Synonyms: Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone
DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
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38
38 Cited Publications
Cat. No.: HY-N0437
CAS No.: 57-83-0
Synonyms: Pregn-4-ene-3,20-dione
Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
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11
11 Cited Publications
Cat. No.: HY-113313
CAS No.: 52-39-1
Purity:  98.93%
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level .
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9
9 Cited Publications
Cat. No.: HY-B0216
CAS No.: 57-63-6
Synonyms: Ethynyl estradiol; 17α-Ethynylestradiol
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .
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7
7 Cited Publications
Cat. No.: HY-13632
CAS No.: 107868-30-4
Purity:  99.83%
Synonyms: FCE 24304; EXE
Target:  

Cytochrome P450

Research Areas:  

Endocrinology Cancer

Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .
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7
7 Cited Publications
Cat. No.: HY-B0151
CAS No.: 145-13-1
Synonyms: 3β-Hydroxy-5-pregnen-20-one
Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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7
7 Cited Publications
Cat. No.: HY-B1739
CAS No.: 1247-64-9
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication . Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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7
7 Cited Publications
Cat. No.: HY-110189
CAS No.: 1852-38-6
Purity:  99.96%
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium
Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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6
6 Cited Publications
Cat. No.: HY-14383
CAS No.: 1182367-47-0
Purity:  99.80%
Synonyms: RAD140; EP0062
Vosilasarm (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a Ki of 7 nM. Vosilasarm shows good selectivity over other steroid hormone nuclear receptors .
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6
6 Cited Publications
Cat. No.: HY-B0742
CAS No.: 630-56-8
Synonyms: 17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate
Target:  

Progesterone Receptor

Research Areas:  

Endocrinology

Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .
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5
5 Cited Publications
Cat. No.: HY-113414
CAS No.: 64-85-7
Purity:  99.61%
Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC50 of 0.16 nM . Deoxycorticosterone could acts as an immune stimulator in fish .
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5
5 Cited Publications
Cat. No.: HY-77839
CAS No.: 152-58-9
Synonyms: 11-Deoxycortisol; cortexolone; Reichstein's substance S
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .
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5
5 Cited Publications
Cat. No.: HY-B0891
CAS No.: 68-96-2
Synonyms: 17-Hydroxyprogesterone; 17-OHP
17α-Hydroxyprogesterone is a steroid hormone. 17α-Hydroxyprogesterone induces ovarian growth and yolk production in female crabs and increases blood pressure in sheep. 17α-Hydroxyprogesterone is mainly used in research related to crustacean reproduction and animal hypertension .
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3
3 Cited Publications
Cat. No.: HY-13604
CAS No.: 427-51-0
Purity:  99.90%
Target:  

Androgen Receptor

Research Areas:  

Endocrinology Cancer

Cyproterone acetate is an anti-androgen (IC50=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors .
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3
3 Cited Publications
Cat. No.: HY-B0141S1
CAS No.: 66789-03-5
Synonyms: β-Estradiol-d4; 17β-Estradiol-d4; 17β-Oestradiol-d4
Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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3
3 Cited Publications
Cat. No.: HY-14598
CAS No.: 56-53-1
Purity:  99.62%
Diethylstilbestrol is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .
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2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
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