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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
synthesize oligonucleotides
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "synthesize oligonucleotides" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-D1668
Cat. No.: HY-P990051
CAS No.: 2653183-66-3
Synonyms: AOC-1001 Antibody; AOC-1044 Antibody
Research Areas:
Delpacibart is a humanized IgG1κ monoclonal antibody targeting the transferrin receptor TFRC. Delpacibart can be conjugated with the phosphorodiamidate morpholino oligonucleotide (PMO) Zotadirsen (HY-177972), which targets exon 44 of the dystrophin gene, to synthesize the antibody-oligonucleotide conjugate (AOC) Delpacibart zotadirsen (HY-177564). Delpacibart is suitable for use in Duchenne muscular dystrophy (DMD44) research .
Research Areas:
5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer used to synthesize locked nucleic acid (LNA) analog oligonucleotides. It can be used as a building block of antisense oligonucleotides (ASOs) to target complementary RNA sequences. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) locks the furanose ring into an N-type conformation through 2',4'-constrained ethyl (cEt) modification, enhancing hybridization affinity and mismatch discrimination with RNA, while significantly improving the resistance of oligonucleotides to exonuclease digestion. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) mediates RNase H-dependent mRNA degradation or inhibits translation by forming a stable hybrid with RNA, thereby achieving gene expression regulation. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is mainly used in the development of antisense drugs, gene function research and oligonucleotide synthesis related to disease treatment .
Cat. No.: HY-21997
CAS No.: 136834-22-5
Cat. No.: HY-173247
CAS No.: 2199491-27-3
Cat. No.: HY-W570888
CAS No.: 206055-69-8
Synonyms: LNA-C(Bz)
Target:
Research Areas:
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands .
Cat. No.: HY-W008351
CAS No.: 24259-59-4
Category:
Target:
Cat. No.: HY-W570891
CAS No.: 206055-78-9
Research Areas:
DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog that can be used to synthesize oligonucleotides .
Cat. No.: HY-78574
CAS No.: 13089-48-0
Target:
Research Areas:
N-Benzoylcytidine is a modified cytidine analogue that can be phosphorylated by uracil-cytidine kinase (UCK1 and UCK2). N-Benzoylcytidine can be used to synthesize 2-OH protective groups for solid-phase RNA synthesis, as well as synthetic oligonucleotides for UV induction and targeted gene silencing in zebrafish embryos .
Cat. No.: HY-W881465
CAS No.: 2172373-55-4
Target:
Research Areas:
5'(E)-VP-2'-OMe-U Phosphoramidite is a phosphoramidite nucleotide precursor compound, mainly used to synthesize stable and functionalized modified oligonucleotides for the research and synthesis of nucleic acid drugs.
Cat. No.: HY-160884
CAS No.: 1470023-72-3
Target:
Research Areas:
DMT-2'-OMe-D-Ribitol phosphoramidite is a phosphoramidite monomer synthesized from (2R,3S,4S)-2-hydroxymethyl-4-methoxytetrahydrofuran-3-ol, used to introduce the Y34 abasic moiety into oligonucleotides for solid-phase oligonucleotide synthesis. DMT-2'-OMe-D-Ribitol phosphoramidite can be used for the research of huntington's disease, machado joseph disease (spinocerebellar ataxia 3) .
Cat. No.: HY-W881466
CAS No.: 2419895-65-9
Target:
Research Areas:
5'(E)-VP-2'-OMe-Bz-A Phosphoramidite is a phosphoramidate nucleotide precursor compound, which is mainly used to synthesize stable and functionalized modified oligonucleotides and is used in the development and synthesis of nucleic acid drugs .
Cat. No.: HY-W1119957
CAS No.: 1882067-09-5
Target:
Research Areas:
5'-VP-2'-OMe-U phosphoramidite is a phosphoramidite that contains 5’ DMT and uridine with 2’-O-methyl protection. 5'-VP-2'-OMe-U Phosphoramidite can be used to synthesize oligonucleotide.
Cat. No.: HY-157091
CAS No.: 497064-75-2
Target:
Research Areas:
Uridine, 5'-(P,P',P'',P''-tetrahydrogen imidotriphosphate) is a non-hydrolyzable nucleotide that can synthesize RNA oligonucleotides .
Cat. No.: HY-W008351S
Cat. No.: HY-W008351R
CAS No.: 24259-59-4
Category:
Cat. No.: HY-185944
CAS No.: 1101239-66-0
Research Areas:
Amino-modifier C3 Phosphoramidite is a modified phosphoramidite monomer that can be used in oligonucleotide synthesis .
Cat. No.: HY-185383
CAS No.: 1280548-97-1
Target:
Research Areas:
SNA G(iBu) amidite is a phosphoramide monomer that can be used to synthesize oligonucleotides.
Cat. No.: HY-185385
CAS No.: 1280548-93-7
Target:
Research Areas:
SNA C(Bz) amidite is a phosphoramide monomer that can be used to synthesize oligonucleotides.
Cat. No.: HY-185386
CAS No.: 1280548-94-8
Target:
Research Areas:
SNA A(Bz) amidite is a phosphoramide monomer that can be used to synthesize oligonucleotides.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
