Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
synthetic chemistry
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "synthetic chemistry" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
1
Target:
Research Areas:
Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death . Norgestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
Cat. No.: HY-W006064
CAS No.: 23235-01-0
Synonyms: (S)-2-Aminopent-4-ynoic acid
Target:
Research Areas:
1
Target:
Research Areas:
Gestrinone (R2323) is a synthetic steroid hormone used to treat endometriosis. It inhibits leiomyoma cells with an IC50 of 43.67 μM. Gestrinone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W013172
CAS No.: 35189-28-7
Target:
Research Areas:
Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive . Norgestimate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W018758
CAS No.: 579-07-7
Category:
Ketones, Aldehydes, Acids Other Diseases Ephedraceae Plants Disease Research Fields Ephedra sinica Stapf
Target:
Cat. No.: HY-134599
CAS No.: 1580501-97-8
Target:
Research Areas:
(2E)-TCO-PNB ester is an active reaction substrate with the properties of trans-cyclooctene derivatives. The core chemical property of (2E)-TCO-PNB ester is its ability to undergo efficient inverse electron-demand Diels-Alder (IEDDA) cycloaddition with tetrazine groups. (2E)-TCO-PNB ester can be used in ligation reactions to verify the integrity of tetrazine groups, and also serves as a key synthetic raw material for the preparation of the prodrug TCO-DOX. (2E)-TCO-PNB ester is applied in research related to drug synthesis and bioorthogonal chemistry .
Synonyms: HE 3286; NE-3107
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target:
Research Areas:
Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
Cat. No.: HY-W010341
CAS No.: 1452-63-7
Target:
Research Areas:
2-Pyridinecarbohydrazide is a versatile heterocyclic building block widely used in medicinal chemistry and coordination chemistry, and it finds extensive applications in various synthetic fields. 2-Pyridinecarbohydrazide reacts with the reducing end of carbohydrates to enhance mass spectrometry ionization efficiency, enabling isomer-specific identification of monosaccharides, disaccharides, ketoses/aldoses, and quantitative mass spectrometry imaging of biological tissues .
Cat. No.: HY-B0257S1
CAS No.: 2376035-98-0
Cat. No.: HY-W005485
CAS No.: 13096-62-3
Synonyms: 2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
Cat. No.: HY-B2091
CAS No.: 17243-38-8
Target:
Research Areas:
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Synonyms: (S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol
Cat. No.: HY-W035133
CAS No.: 14527-51-6
Synonyms: 5,10,15,20-Tetra-p-tolyl-21H,23H-porphine
Synonyms: L-azidovaline CHA
Target:
Research Areas:
N3-L-Val-OH (L-azidovaline) (CHA) is a mixture of N3-L-Val-OH and Cyclohexanamine. N3-L-Val-OH is a non-natural amino acid building block specifically designed for solid-phase peptide synthesis and click chemistry. N3-L-Orn(Fmoc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
Cat. No.: HY-W014159
CAS No.: 55289-35-5
Cat. No.: HY-Y0837S
CAS No.: 352438-84-7
Synonyms: (S)-2-Amino-1-propanol-d3; (S)-2-Aminopropanol-d3; (S)-Alaninol-d3
Cat. No.: HY-W127342
CAS No.: 112-13-0
Synonyms: Decanoic acid chloride
Target:
Research Areas:
Decanoyl chloride is an organic compound belonging to the class of acid chlorides. It is a colorless liquid with a pungent odor and is commonly used as a reagent in various organic chemical reactions, especially in the synthesis of esters, amides and fatty acids. Decanoyl chloride has numerous applications in synthetic organic chemistry, especially in the production of pharmaceuticals, agrochemicals and specialty chemicals. In addition, it can be used as a precursor for the synthesis of surfactants and detergents.
Cat. No.: HY-W095635
CAS No.: 17787-40-5
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
