2749-11-3
Chemical Structure
L-Alaninol
Synonym(s): (S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol
- CAS No.: 2749-11-3
- Formula:C3H9NO
- Molecular Weight:75.11
IUPAC Name: (S)-2-aminopropan-1-ol
InChIKey: BKMMTJMQCTUHRP-VKHMYHEASA-N
SMILES: C[C@H](N)CO
Biological Activity: L-Alaninol ((S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol) is a chiral amino alcohol that serves as a precursor for Levofloxacin (HY-B0330) and Metolachlor (HY-B1871). L-Alaninol acts as the sole carbon source for Pseudomonas sp. strain KIE171, and it is a metabolite produced by the hydrolysis of γ-glutamyl-L-alaninol. L-Alaninol functions as a substrate for oxidative/deaminative degradation and undergoes enzymatic glutamylation via IpuC. It is used as a synthetic building block in the fields of agriculture, pharmaceuticals, and peptide chemistry, and also serves as a chiral auxiliary[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Alaninol | 99.91% | L-Alaninol ((S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol) is a chiral amino alcohol that serves as a precursor for Levofloxacin (HY-B0330) and Metolachlor (HY-B1871). L-Alaninol acts as the sole carbon source for Pseudomonas sp. strain KIE171, and it is a metabolite produced by the hydrolysis of γ-glutamyl-L-alaninol. L-Alaninol functions as a substrate for oxidative/deaminative degradation and undergoes enzymatic glutamylation via IpuC. It is used as a synthetic building block in the fields of agriculture, pharmaceuticals, and peptide chemistry, and also serves as a chiral auxiliary. | ||||||||||||||||||||
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L-Alaninol-d3 | 98.0% | L-Alaninol-d3 ((S)-2-Amino-1-propanol-d3; (S)-2-Aminopropanol-d3; (S)-Alaninol-d3) is the deuterated-labeled L-Alaninol (HY-Y0837). L-Alaninol ((S)-2-Amino-1-propanol; (S)-2-Aminopropanol; (S)-Alaninol) is a chiral amino alcohol that serves as a precursor for Levofloxacin (HY-B0330) and Metolachlor (HY-B1871). L-Alaninol acts as the sole carbon source for Pseudomonas sp. strain KIE171, and it is a metabolite produced by the hydrolysis of γ-glutamyl-L-alaninol. L-Alaninol functions as a substrate for oxidative/deaminative degradation and undergoes enzymatic glutamylation via IpuC. It is used as a synthetic building block in the fields of agriculture, pharmaceuticals, and peptide chemistry, and also serves as a chiral auxiliary. | ||||||||||||||||||||
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- [1]. Benninghaus L, et al. γ-Glutamylation of Isopropylamine by Fermentation. Chembiochem : a European journal of chemical biology. 2024 Jan 15;25(2):e202300608. [Content Brief]
- [2]. de Azevedo Wäsch SI, et al. Transformation of isopropylamine to L-alaninol by Pseudomonas sp. strain KIE171 involves N-glutamylated intermediates. Applied and environmental microbiology. 2002 May;68(5):2368-75. [Content Brief]
- [3]. Jere FT, et al. Stereoretentive C–H Bond Activation in the Aqueous Phase Catalytic Hydrogenation of Amino Acids to Amino Alcohols. Org Lett. 2003;5(4):527-530.
Keywords
