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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
tau-protein
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "tau-protein" in MCE Product Catalog:
6
6 Publications Verification
Cat. No.: HY-19948
CAS No.: 1236208-20-0
Synonyms: TRx0237 mesylate; Methylene blue leuco base mesylate
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PhosTAC7 is a heterobifunctional molecule named as a Phosphorylation Targeting Chimera (PhosTAC). PhosTAC7 can dephosphorylate the PDCD4 protein, FOXO3a protein, and tau protein by recruiting serine/threonine protein phosphatase 2A (PP2A). PhosTAC7 offers the advantage of selectively modulating the phosphorylation state of individual target proteins, making it a promising tool for research in cancer and tau protein-related neurodegenerative diseases (Alzheimer's disease) .
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Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Simufilam (PTI-125) is an orally active FLNA modulator. Simufilam restores NMDAR signaling and Arc expression. Simufilam inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation.
Simufilam can be used for research of Alzheimer's disease .
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1 Cited Publications
Synonyms: PTI-125 hydrochloride
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Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. Simufilam hydrochloride restores NMDAR signaling and Arc expression. Simufilam hydrochloride inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation. Simufilam hydrochloride can be used for research of Alzheimer's disease .
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1 Cited Publications
Cat. No.: HY-N0695
CAS No.: 58546-55-7
Synonyms: Gomisin-B; Wuweizi ester-B; Schisantherin-B
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PBB3 is a tracer of tau PET. PBB3 can be used to detect levels of tau protein in Alzheimer's disease and non-Alzheimer's disease .
Cat. No.: HY-P99471
CAS No.: 2244960-75-4
Synonyms: UCB 0107
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Cat. No.: HY-P4808
CAS No.: 329897-62-3
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Cat. No.: HY-P990995
CAS No.: 2690265-18-8
Synonyms: E2814
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C004019 is a BBB-penetrable and small-molecule PROTAC that targets tau. C004019 can simultaneously recruit tau and E3 ligase, and effectively clear tau proteins by promoting the ubiquitination and proteasome-dependent degradation of tau, thereby improving synaptic and cognitive functions in Alzheimer's disease (AD) mice. C004019 can be used in the research of AD and tau protein-related diseases .
Cat. No.: HY-101185
CAS No.: 1320211-61-7
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T808 is a selective tau protein-targeting ligand. T808 can be used to synthesize [ 18F]-T808, a highly selective tau protein positron emission tomography (PET) tracer. T808 can also be used to synthesize [ 3H]-T808, a marker for in vitro experiments. T808 can be used for the research of alzheimer’s disease .
Cat. No.: HY-P99399
CAS No.: 2159141-27-0
Synonyms: RG 6100; RO7105705; Mtau-9937A
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Cat. No.: HY-P991480
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Cat. No.: HY-P1707A
CAS No.: 2703746-44-3
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Cat. No.: HY-P99648
CAS No.: 1788032-39-2
Synonyms: BMS-986168; IPN007; BIIB092
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Cat. No.: HY-132582
CAS No.: 2304711-06-4
Synonyms: IONIS-MAPTRx; BIIB080; ISIS 814907
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Diranersen (IONIS-MAPTRx) is an antisense oligonucleotide that targets the human MAPT gene to inhibit the production of tau protein. Diranersen can be used in research related to Alzheimer's disease and tauopathies .
Cat. No.: HY-132582C
Purity: 91.82%
Synonyms: IONIS-MAPTRx sodium; BIIB080 sodium; ISIS 814907 sodium
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Diranersen (IONIS-MAPTRx) sodium is an antisense oligonucleotide that targets the human MAPT gene to inhibit the production of tau protein. Diranersen sodium can be used in research related to Alzheimer's disease and tauopathies .
Cat. No.: HY-P9995
CAS No.: 2517973-04-3
Synonyms: JNJ-63733657
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Cat. No.: HY-W453397
CAS No.: 1892461-96-9
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Aberrant tau ligand 1 is a tau protein ligand. Aberrant tau ligand 1 engages tau and CRBN to trigger proteasomal degradation. Aberrant tau ligand 1 can be used for synthesis PROTACs, such as QC-01–175 (HY-134850) .
Cat. No.: HY-P99163
CAS No.: 2096513-89-0
Synonyms: ABBV-8E12; C2N-8E12
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
