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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
ubiquitin-like protein
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "ubiquitin-like protein" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P80351
Synonyms: DAP1 antibody;
GAP modifying protein 1 antibody;
GMP 1 antibody;
OFC10 antibody;
PIC 1 antibody;
PIC1 antibody;
SENP2 antibody;
Sentrin 1 antibody;
Sentrin antibody;
Small ubiquitin related modifier 1 antibody;
Small ubiquitin-like modifier 1 antibody;
Small ubiquitin-related modifier 1 antibody;
SMT3 antibody;
SMT3 homolog 3 antibody;
SMT3 suppressor of mif two 3 homolog 1 antibody;
SMT3, yeast, homolog 3 antibody;
Smt3C antibody;
SMT3H3 antibody;
SUMO-1 antibody;
SUMO1 antibody;
SUMO1_HUMAN antibody;
ubiquitin homology domain protein PIC1 antibody;
ubiquitin like 1 antibody;
ubiquitin like protein SMT3C antibody;
ubiquitin like protein UBL1 antibody;
ubiquitin-homology domain protein PIC1 antibody;
ubiquitin-like protein SMT3C antibody;
ubiquitin-like protein UBL1 antibody;
UBL 1 antibody;
UBL1 antibody
2
2 Cited Publications
Cat. No.: HY-P74485
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBA1; ubiquitin like Modifier Activating Enzyme 1; A1S9T; UBE1; GXP1; ubiquitin-like Modifier-Activating Enzyme 1; ubiquitin-Activating Enzyme E1; CFAP124; UBE1X; POC20; ubiquitin-Activating Enzyme E1 (A1S9T And BN75 Temperature Sensitivity Complementing)
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Cat. No.: HY-P80240
Synonyms: FLJ43224 antibody;
MGC104393 antibody;
MGC125896 antibody;
MGC125897 antibody;
NED8 antibody;
NEDD 8 antibody;
NEDD-8 antibody;
Nedd8 antibody;
NEDD8_HUMAN antibody;
Neddylin antibody;
Neural precursor cell expressed developmentally down regulated 8 antibody;
Neural precursor cell expressed developmentally down regulated gene 8 antibody;
Neural precursor cell expressed developmentally down-regulated protein 8 antibody;
Rub1 antibody;
ubiquitin like protein Nedd 8 antibody;
ubiquitin like protein Nedd8 antibody;
ubiquitin-like protein Nedd8 antibody;
1
1
1
Cat. No.: HY-169179
CAS No.: 2984505-88-4
AK-1690 is a selective PROTAC degrader targeting STAT6 (DC50=1 nM) with a Ki of 6 nM against human STAT6. AK-1690 degrades STAT6 via the interaction of STAT6 with cereblon and a ubiquitin-like process. AK-1690 effectively depletes STAT6 protein in mouse liver and lung tissues, and is applicable to research related to leukemia, Hodgkin's lymphoma, follicular lymphoma, etc. .
Target:
Research Areas:
SHP2-D26 isomer-1 (Compound 26) is an isomer of SHP2-D26 (HY-145162). SHP2-D26 is the first highly potent SHP2 PROTAC degrader. The induction of SHP2 degradation by SHP2-D26 requires binding to VHL-1 and SHP2 proteins, and is dependent on ubiquitin-like modification and the proteasome. SHP2-D26 can be used in the research of esophageal cancer and acute myeloid leukemia .
Cat. No.: HY-170824
CAS No.: 3033586-31-8
Target:
Research Areas:
SMD-3236 is a SMARCA2 PROTAC degrader with a DC50 of 0.5 nM, a Dmax of 98%, and an IC50 of 42.2 nM against human SMARCA2. SMD-3236 induces proteasome- and ubiquitin-like modification-dependent degradation of SMARCA2 protein by binding to SMARCA2 and VHL-1. SMD-3236 inhibits the growth of SMARCA4-deficient cancer cells. SMD-3236 induces significant and persistent depletion of SMARCA2 in tumor tissues. SMD-3236 suppresses tumor growth in SMARCA4-deficient human cancer xenograft models. SMD-3236 can be used in research related to SMARCA4-deficient cancers such as melanoma, non-small cell lung cancer, and acute myeloid leukemia .
Cat. No.: HY-E70372
CAS No.: 1607459-82-4
Target:
Research Areas:
SUMO Protease is highly specific for proteins containing small ubiquitin-like modifier (SUMO) tags. SUMO Protease can be used to regulates the proteins splicing, controlls protein structure and function in vitro .
Cat. No.: HY-D1546
CAS No.: 139554-72-6
Cat. No.: HY-178458
Target:
Research Areas:
UBA5-IN-2 (Compound 50) is a potent ubiquitin-like modifier activating enzyme 5 (UBA5) inhibitor (IC50=0.063 μM). UBA5-IN-2 is promising for research of cancers and protein homeostasis-related diseases .
Cat. No.: HY-P3830
Target:
Research Areas:
Cat. No.: HY-163105
CAS No.: 3072778-26-5
Target:
Research Areas:
Tubulin/NEDDylation-IN-1 (compound C11) is a dual inhibitor of tubulin (Microtubule/Tubulin)-NEDDylation (IC50 for tubulin=2.40 μM), which has strong anti-proliferative activity. Neddylation is a protein post-translational modification that covalently tags the ubiquitin-like protein NEDD8 to target proteins. Tubulin/NEDDylation-IN-1 forms hydrogen bonds with residues of tubulin and E1 NEDD8 activating enzyme (NAE) through methoxy and dithiocarbamate groups and inhibits NEDDylation and microtubulin in an ATP-dependent manner. tube polymerization .
Cat. No.: HY-P86396
Synonyms: SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; ubiquitin-homology domain protein PIC1; ubiquitin-like protein SMT3C; Smt3C; ubiquitin-like protein
Cat. No.: HY-P77251
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TMUB2; MGC3123; Transmembrane And ubiquitin like Domain Containing 2; Transmembrane And ubiquitin-like Domain Containing 2; Transmembrane And ubiquitin-like Domain-Containing protein 2; FP2653
Species:
Human
Source:
HEK293
Cat. No.: HY-P703607
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBA2; SAE2; UBLE1B; HRIHFB2115; SUMO-activating enzyme subunit 2; EC 2.3.2.-; Anthracycline-associated resistance ARX; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier-activating enzyme 2
Species:
Human
Source:
E. coli
Cat. No.: HY-P702947
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: UBA2; SAE2; UBLE1B; HRIHFB2115; SUMO-activating enzyme subunit 2; EC 2.3.2.-; Anthracycline-associated resistance ARX; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier-activating enzyme 2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703608
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBA2; SAE2; UBLE1B; HRIHFB2115; SUMO-activating enzyme subunit 2; EC 2.3.2.-; Anthracycline-associated resistance ARX; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier-activating enzyme 2
Species:
Human
Source:
E. coli
Cat. No.: HY-P71643
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SAE1; SUMO-1 Activating Enzyme Subunit 1, Isoform CRA_a; SUMO1 Activating Enzyme Subunit 1; ubiquitin-like protein SUMO-1 Activating Enzyme; AOS1; SUMO-1 Activating Enzyme E1 N Subunit; Sua1; Sentrin/SUMO-Activating protein AOS1; ubiquitin-like 1-Activati
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
