1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. UBA5-IN-2

UBA5-IN-2 (Compound 50) is a potent ubiquitin-like modifier activating enzyme 5 (UBA5) inhibitor (IC50=0.063 μM). UBA5-IN-2 is promising for research of cancers and protein homeostasis-related diseases.

For research use only. We do not sell to patients.

UBA5-IN-2

UBA5-IN-2 Chemical Structure

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Description

UBA5-IN-2 (Compound 50) is a potent ubiquitin-like modifier activating enzyme 5 (UBA5) inhibitor (IC50=0.063 μM). UBA5-IN-2 is promising for research of cancers and protein homeostasis-related diseases[1].

Molecular Weight

644.74

Formula

C35H41FN6O5

SMILES

CN(C(CNC(C1=C2C=CC=NC2=CC=C1)=O)=O)[C@H]3CCCN(C4=C(C=C(C5=C4C(C)=C(N5C)C)C(N[C@@H]6COCC[C@H]6O)=O)F)C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
UBA5-IN-2
Cat. No.:
HY-178458
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