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Pathways Recommended:	Vitamin D Related/Nuclear Receptor

Results for "

vitamin D3 receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	VD/VDR (26) Apoptosis (1) Aryl Hydrocarbon Receptor (2) Autophagy (2) Biochemical Assay Reagents (1) Cytochrome P450 (1) Drug Derivative (1) Drug Metabolite (3) Endogenous Metabolite (7) Isotope-Labeled Compounds (9) LXR (1) NF-κB (1) PPAR (3) RAR/RXR (3) Reference Standards (1)
By Research Areas:	Cancer (11) Endocrinology (2) Infection (1) Inflammation/Immunology (4) Metabolic Disease (13)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: VD/VDR VKOR

Art. -Nr.	Produktname	Target	Forschungsgebiete	Chemical Structure

HY-32343

Secalciferol 5+ Cited Publications (24R)-24,25-Dihydroxyvitamin D3	Endogenous Metabolite VD/VDR	Metabolic Disease Inflammation/Immunology
Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC₅₀ value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .

HY-76814

Calcitriol-d6	VD/VDR Isotope-Labeled Compounds	Metabolic Disease
Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR) .

HY-12398

TEI-9647 2 Publications Verification	VD/VDR	Metabolic Disease Inflammation/Immunology
TEI-9647, a Vitamin D₃ Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)₂D₃. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)₂D₃. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease .

HY-N10508

Calcitroic acid	Drug Metabolite VD/VDR	Metabolic Disease Cancer
Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

HY-12397

ZK159222 1 Publications Verification	VD/VDR	Endocrinology
ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent *1α,25-(OH)2D3 receptor* (VDR)** antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character .

HY-10002A

(1S)-Calcitriol 1α,25-Dihydroxy-3-epi-vitamin-D3	VD/VDR	Others
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D₃ (1α,25(OH)₂D₃). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-32344

Inecalcitol 1 Publications Verification TX 522	VD/VDR Apoptosis	Cancer
Inecalcitol (TX 522), a unique vitamin D3 analog, is an orally active vitamin D receptor (VDR) agonist with a K_d of 0.53 nM. Inecalcitol can induce cell apoptosis and has potent anticancer activities . Inecalcitol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-12398A

TEI-9648 1 Publications Verification	VD/VDR	Metabolic Disease Inflammation/Immunology
TEI-9648, a Vitamin D₃ Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)₂D₃. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)₂D₃. TEI-9648 has the potential for bone metabolism research .

HY-77278

25-Hydroxytachysterol3	VD/VDR Aryl Hydrocarbon Receptor LXR PPAR	Others
25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor (VDR) and aryl hydrocarbon receptor (AhR), liver X receptor α/β (LXR α/β) and peroxisome proliferator-activated receptor γ (PPARγ), stimulates the expression of CYP24A1 .

HY-154825

20-Hydroxyvitamin D3 20(OH)D3; 20S-Hydroxyvitamin D3	VD/VDR Aryl Hydrocarbon Receptor NF-κB Cytochrome P450	Inflammation/Immunology Cancer
20-Hydroxyvitamin D3 (20(OH)D3), a product of vitamin D3 hydroxylation, is a noncalcemic immunomodulator. 20-Hydroxyvitamin D3 binds to vitamin D receptor (VDR), activates VDR and aryl hydrocarbon receptor (AhR) signaling, stimulates CYP24A1 expression, and drives VDR nuclear translocation. 20-Hydroxyvitamin D3 inhibits NF-κB activity via IκBα upregulation. 20-Hydroxyvitamin D3 acts as a substrate for CYP27B1 and rat CYP24A1, undergoing hydroxylation to form dihydroxy-derivatives. 20-Hydroxyvitamin D3 inhibits cell proliferation, colony formation, migration, and tumor growth, and induces cell differentiation in cancer cells. 20-Hydroxyvitamin D3 can be used for the research of inflammatory and autoimmune diseases, melanoma, breast carcinomas, and hepatocarcinoma .

HY-13292

Impurity B of Calcitriol 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol	VD/VDR	Cancer
Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-10002S1

Calcitriol-d3 1,25-Dihydroxyvitamin D3-d₃	VD/VDR Endogenous Metabolite	Cancer
Calcitriol-d₃ is the deuterium labeled Calcitriol . Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist .

HY-75041

Calcitriol Impurities A	Biochemical Assay Reagents	Metabolic Disease
Calcitriol Impurities A is an impurity of Calcitriol (HY-10002). Calcitriol is the active metabolite of vitamin D3 and can activate the vitamin D receptor.

HY-107218

11-Hydroxysugiol	RAR/RXR VD/VDR	Infection
11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D₃ receptor (VDR) .

HY-77274

Calcitriol Impurities D	VD/VDR	Metabolic Disease
Calcitriol Impurities D is the impurity of Calcitriol, Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-13293

Impurity C of Calcitriol	VD/VDR	Cancer
Impurity C of Calcitriol is the impurity of Calcitriol (HY-10002). Calcitriol is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-15329

Maxacalcitol-d6	VD/VDR	Metabolic Disease
Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.

HY-10002B

(1R,5Z)-Calcitriol (1R,5Z)-1,25-Dihydroxyvitamin D3	VD/VDR	Cancer
(1R,5Z)-Calcitriol ((1R,5Z)-1,25-Dihydroxyvitamin D3) is a Calcitriol (HY-10002) isomer. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist .

HY-32350S1

Ercalcitriol-d3 1α,25-Dihydroxy vitamin D2-d₃	Isotope-Labeled Compounds Endogenous Metabolite VD/VDR	Metabolic Disease
Ercalcitriol-d₃ (1α,25-Dihydroxy Vitamin D2-d₃) is the deuterium labeled Ercalcitriol (HY-32350). Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

HY-14649S5

Retinoic acid-d3 vitamin A acid-d₃; all-trans-Retinoic acid-d₃; ATRA-d₃	Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
Retinoic acid-d₃ is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S6

Retinoic acid-d3-1 vitamin A acid-d₃-1; all-trans-Retinoic acid-d₃-1; ATRA-d₃-1	Isotope-Labeled Compounds RAR/RXR PPAR Endogenous Metabolite Autophagy	Metabolic Disease Cancer
Retinoic acid-d₃-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-10002AS

(1S)-Calcitriol-d3 1α,25-Dihydroxy-3-epi-vitamin D3-d₃	Isotope-Labeled Compounds VD/VDR	Others
(1S)-Calcitriol-d₃ (1α,25-Dihydroxy-3-epi-vitamin D3-d₃) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-15364

19-nor-1α,25-Dihydroxyvitamin D3	Drug Derivative VD/VDR	Metabolic Disease
19-nor-1α,25-Dihydroxyvitamin D3 is a vitamin D receptor (VDR) agonist with an EC₅₀ of 4.8 nM. 19-nor-1α,25-Dihydroxyvitamin D3 binds to VDR and promotes gene transcription. 19-nor-1α,25-Dihydroxyvitamin D3 can be used in the research of diseases related to the vitamin D signaling pathway .

HY-10002S2

Calcitriol-d9 1,25-Dihydroxyvitamin D3-d₉	Isotope-Labeled Compounds VD/VDR Drug Metabolite Endogenous Metabolite	Cancer
Calcitriol-d₉ (1,25-Dihydroxyvitamin D3-d₉) is the deuterium labeled Calcitriol (HY-10002). Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

HY-10002AS2

(1S)-Calcitriol-d6 1α,25-Dihydroxy-3-epi-vitamin D3-d₆	Isotope-Labeled Compounds VD/VDR	Others
(1S)-Calcitriol-d₆ (1α,25-Dihydroxy-3-epi-vitamin D3-d₆) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-10002AR

(1S)-Calcitriol (Standard) 1α,25-Dihydroxy-3-epi-vitamin-D3 (Standard)	Reference Standards VD/VDR	Others
(1S)-Calcitriol (Standard) is the analytical standard of (1S)-Calcitriol (HY-10002A). This product is intended for research and analytical applications. (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-N10508S

Calcitroic acid-13C	Isotope-Labeled Compounds VD/VDR Drug Metabolite	Metabolic Disease Cancer
Calcitroic acid- ¹³C is the ¹³C-labeled Calcitroic acid (HY-N10508). Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

HY-131492S

Δ4-Dafachronic Acid-d3	Isotope-Labeled Compounds Endogenous Metabolite VD/VDR	Metabolic Disease
Δ4-Dafachronic Acid-d₃ is deuterium labeled Δ4-Dafachronic acid (HY-131492). Δ4‑Dafachronic acid is an endogenous steroid hormone, an agonist of the DAF‑12 nuclear receptor, and a key ligand for the vitamin D receptor (VDR). Δ4‑Dafachronic acid promotes the active escape developmental trajectory in Austrofundulus limnaeus embryos even under diapause‑inducing conditions. Δ4‑Dafachronic acid is suitable for research on the developmental biology .

HY-180503

19-Nor-22-oxa-1a,25(OH)2-VD3	VD/VDR	Endocrinology
19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue. 19-Nor-22-oxa-1a,25(OH)2-VD3 has an extremely low affinity for the vitamin D receptor (VDR) and hardly binds to the vitamin D binding protein (DBP). 19-Nor-22-oxa-1a,25(OH)2-VD3 can effectively induce the differentiation of HL-60 cells and cause G₀-G₁ phase cell cycle arrest. 19-Nor-22-oxa-1a,25(OH)2-VD3 can be used to study diseases such as excessive hyperparathyroidism .

Art. -Nr.	Produktname	Category	Target	Chemical Structure

HY-32343

Secalciferol 5+ Cited Publications (24R)-24,25-Dihydroxyvitamin D3	Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids Source Classification	Endogenous Metabolite VD/VDR
Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC₅₀ value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .

HY-N10508

Calcitroic acid	Ketones, Aldehydes, Acids Endogenous metabolite	Drug Metabolite VD/VDR
Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

Species:	Human (1) Mouse (1)
Tag:	His (2)
Source:	Sf9 insect cells (2)

Art. -Nr.	Compare	Produktname	Species	Source	Image

HY-P73542

	Vitamin D Receptor/VDR Protein, Mouse (sf9, His) vitamin D3 receptor; VDR; NR1I1	Mouse	Sf9 insect cells
	Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol, which translocates to the nucleus after binding vitamin D3, thereby coordinating cellular activities.VDR forms a heterodimer with RXR, binds to DNA response elements, and initiates the transcription of vitamin D3-responsive genes.Vitamin D Receptor/VDR Protein, Mouse (sf9, His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P73543

	Vitamin D Receptor/VDR Protein, Human (sf9, His) vitamin D3 receptor; VDR; NR1I1	Human	Sf9 insect cells
	Vitamin D receptor (VDR) acts as a nuclear receptor for calcitriol, the active form of vitamin D3, triggering cellular effects. After vitamin D3 binding, VDR translocates to the nucleus and forms a heterodimer with the retinoid X receptor (RXR). Vitamin D Receptor/VDR Protein, Human (sf9, His) is the recombinant human-derived Vitamin D Receptor/VDR protein, expressed by Sf9 insect cells , with C-10*His labeled tag.

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Art. -Nr.	Produktname	Chemical Structure

HY-76814

Calcitriol-d6
Calcitriol-d₆ is the deuterium labeled Calcitriol. Calcitriol is the active metabolite of vitamin D3 and an agonist of the vitamin D receptor (VDR) .

HY-10002S1

Calcitriol-d3
Calcitriol-d₃ is the deuterium labeled Calcitriol . Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist .

HY-15329

Maxacalcitol-d6
Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.

HY-32350S1

Ercalcitriol-d3
Ercalcitriol-d₃ (1α,25-Dihydroxy Vitamin D2-d₃) is the deuterium labeled Ercalcitriol (HY-32350). Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

Ercalcitriol-d3

Ercalcitriol-d₃ (1α,25-Dihydroxy Vitamin D2-d₃) is the deuterium labeled Ercalcitriol (HY-32350). Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

HY-14649S5

Retinoic acid-d3
Retinoic acid-d₃ is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

Retinoic acid-d3

Retinoic acid-d₃ is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-14649S6

Retinoic acid-d3-1
Retinoic acid-d₃-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

Retinoic acid-d3-1

Retinoic acid-d₃-1 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha .

HY-10002AS

(1S)-Calcitriol-d3
(1S)-Calcitriol-d₃ (1α,25-Dihydroxy-3-epi-vitamin D3-d₃) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

(1S)-Calcitriol-d3

(1S)-Calcitriol-d₃ (1α,25-Dihydroxy-3-epi-vitamin D3-d₃) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-10002S2

Calcitriol-d9
Calcitriol-d₉ (1,25-Dihydroxyvitamin D3-d₉) is the deuterium labeled Calcitriol (HY-10002). Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

HY-10002AS2

(1S)-Calcitriol-d6

(1S)-Calcitriol-d₆ (1α,25-Dihydroxy-3-epi-vitamin D3-d₆) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-N10508S

Calcitroic acid-13C
Calcitroic acid- ¹³C is the ¹³C-labeled Calcitroic acid (HY-N10508). Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

HY-131492S

Δ4-Dafachronic Acid-d3

Δ4-Dafachronic Acid-d₃ is deuterium labeled Δ4-Dafachronic acid (HY-131492). Δ4‑Dafachronic acid is an endogenous steroid hormone, an agonist of the DAF‑12 nuclear receptor, and a key ligand for the vitamin D receptor (VDR). Δ4‑Dafachronic acid promotes the active escape developmental trajectory in Austrofundulus limnaeus embryos even under diapause‑inducing conditions. Δ4‑Dafachronic acid is suitable for research on the developmental biology .

Host:	Mouse (1) Rabbit (2)
Reactivity:	Human (3) Mouse (1) Rat (2)
Application:	IHC-P (2) ICC/IF (3) IHC-F (1) WB (2) ELISA (1)
Isotype:	IgG (2) IgG1 (1)
Conjugation:	Non-conjugated (3)
Clonality:	Polyclonal (1) Monoclonal (2) Recombinant (1)
Modification:	Unmodified (3)

Art. -Nr.	Compare	Produktname	Application	Reactivity	Image

HY-P85862

	Vitamin D Receptor Antibody (YA5554) vitamin D3 receptor; VDR; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1;	WB, ICC/IF, ELISA	Human
	Vitamin D Receptor Antibody (YA5554) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Vitamin D Receptor.

HY-P81203

	Vitamin D Receptor Antibody 1 Publications Verification vitamin D3 receptor; 125 dihydroxyvitamin D3 receptor; 1 antibody 1,25-@dihydroxyvitamin D3 receptor; 125 dihydroxyvitamin D3 receptor; 25-dihydroxyvitamin D3 receptor; NR1I1; Nuclear receptor subfamily 1 group I member 1; VDR; VDR_HUMAN; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D hormone receptor; vitamin D receptor; vitamin D3 receptor,	IHC-P, IHC-F, ICC/IF	Human, Rat
	Vitamin D Receptor Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Vitamin D Receptor.

HY-P86960

	MED4 Antibody (YA6653) Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPC126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPC126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; OTTHUMP00000018390 antibody; OTTHUMP00000018391 antibody; OTTHUMP00000018392 antibody; RP11-90M2.2 antibody; TRAP/SMCC/PC2 subunit p36 subunit antibody; TRAP36 antibody; VDR; IP : antibody; vitamin D3 receptor-interacting protein complex 36 kDa component antibody;	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	MED4 Antibody (YA6653) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MED4.

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