Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
voltage-sensitive sodium channel
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "voltage-sensitive sodium channel" in MCE Product Catalog:
9
Research Areas:
Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
6
Target:
Research Areas:
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS.
3
3 Cited Publications
Target:
Research Areas:
PD173212 is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays.
2
1
Research Areas:
Tetracaine hydrochloride (Amethocaine hydrochloride) is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca 2+ from sarcoplasmic reticulum. Tetracaine hydrochloride is mainly used topically in ophthalmology and as an antipruritic .
1
Target:
Target:
Cat. No.: HY-12650S1
Synonyms: DS5565-d4
Cat. No.: HY-B0122R
CAS No.: 97240-79-4
Synonyms: McN 4853 (Standard); RWJ 17021 (Standard)
Target:
Reference Standards iGluR GABA Receptor Sodium Channel Calcium Channel Potassium Channel Carbonic Anhydrase
Research Areas:
Topiramate (Standard) is the analytical standard of Topiramate. This product is intended for research and analytical applications. Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
Cat. No.: HY-P3269
CAS No.: 178805-91-9
Target:
Research Areas:
Cat. No.: HY-B0122S
Synonyms: McN 4853-13C6; RWJ 17021-13C6
Cat. No.: HY-111157
CAS No.: 91077-32-6
Synonyms: AHR11748; AN051; ADD94057
Cat. No.: HY-W042039
CAS No.: 15964-79-1
Target:
Research Areas:
Methyl homoveratrate, a metabolite of RWJ-26240 in vivo, can be identified in plasma, urine and faecal extract. McN5691 (RWJ-26240) is a voltage-sensitive calcium channel blocker .
Cat. No.: HY-133195
CAS No.: 13669-70-0
Synonyms: Fenazoxine
Target:
Research Areas:
Nefopam (Fenazoxine) is an orally active, non-opioid and non-steroidal centrally acting analgesic agent. Nefopam blocks voltage-sensitive sodium channels (IC50=27 μM) and modulates glutamatergic transmission in rodents. Nefopam can be used in studies of neuropathic pain, anticonvulsant, as well as the prevention of postoperative shivering and hiccups .
Cat. No.: HY-110234
CAS No.: 1279037-95-4
Synonyms: McN 4853 D12 ; RWJ 17021 D12
Research Areas:
Topiramate D12 (McN 4853 D12) is a deuterium labeled Topiramate. Topiramate is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
Cat. No.: HY-12650S
Synonyms: DS5565-13C2,d1 (Mixture of Diastereomers)
Cat. No.: HY-U00218
CAS No.: 99254-95-2
Synonyms: RWJ26240
Target:
Research Areas:
McN5691 is a voltage-sensitive calcium channel blocker.
Cat. No.: HY-U00388
CAS No.: 313653-15-5
Target:
Research Areas:
α2δ ligand 1 is a ligand to the α2δ-1 subunit of voltage-sensitive calcium channel, extracted from patent US20040186177.
Target:
Research Areas:
Tetracaine (hydrochloride) (Standard) is the analytical standard of Tetracaine (hydrochloride). This product is intended for research and analytical applications. Tetracaine hydrochloride (Amethocaine hydrochloride) is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride is mainly used topically in ophthalmology and as an antipruritic .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
