STING-IN-14
STING-IN-14 is an inhibitor of STING (IC50: 0.6 nM). STING-IN-14 inhibits the activation of the IRF pathway in THP1-DualTM cells. STING-IN-14 can be used in autoimmune diseases research.
For research use only. We do not sell to patients.
- CAS No.: 3070953-78-2
- Formula: C46H43F2N11O5
- Molecular Weight:867.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
STING-IN-14 (Example 50) (20-24 h) inhibits the activation of IRF pathway in THP1-DualTM cells (IC50: 2 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3070953-78-2
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Molecular Weight 867.90
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Formula C46H43F2N11O5
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SMILES
[H][C@]1(C(NC[C@@H](C(NCC2=CC=CC=C2)=O)NC([C@]3([H])C[C@@](O4)([H])CN3C5=NC=NC6=C5C=NN6C7=C(F)C=C(F)C=C7)=O)=O)N(CCN8N=C(C=CC=C9C%10=CC=CC4=C%10)C9=C8)CCOC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)