Streptimidone
Streptimidone (Ao58A) is a bacterial metabolite found in Streptomyces. Streptimidone has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 738-72-7
- Formula: C16H23NO4
- Molecular Weight:293.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 738-72-7
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Molecular Weight 293.36
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Formula C16H23NO4
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SMILES
C=C/C(C)=C/[C@H](C)C(C[C@H](O)CC1CC(NC(C1)=O)=O)=O
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Synonyms
Ao58A; NSC 66645
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Structure Classification
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Initial Source
Streptomyces platensis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.
Purity & Documentation
References
[1]. Bennett LL Jr, et al. Inhibition of protein synthesis in vitro by cycloheximide and related glutarimide antibiotics. Biochim Biophys Acta. 1965 Jul 15;103(3):478-85. [Content Brief]
[2]. TELLER MN. Antibiotics in experimental cancer chemotherapy. Trans N Y Acad Sci. 1961 Dec;24:158-66. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)