1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Terazosin hydrochloride

Terazosin hydrochloride 

Cat. No.: HY-B0371F
Handling Instructions

Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment.

For research use only. We do not sell to patients.

Terazosin hydrochloride Chemical Structure

Terazosin hydrochloride Chemical Structure

CAS No. : 63074-08-8

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Description

Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment[1][2][3].

IC50 & Target

α1-adrenoceptor[1]

In Vitro

Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Terazosin can be used to promote stone discharge in treatment of ureteral stones. Terazosin is reportedly safe and effective in treatment of distal ureteral stones, especially stones >5 mm[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

423.89

Formula

C₁₉H₂₆ClN₅O₄

CAS No.

63074-08-8

SMILES

O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OCCC4.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TerazosinAdrenergic ReceptorBeta Receptorα1-adrenoceptorbenignprostatichyperplasiahighbloodpressurebladderquinazolineInhibitorinhibitorinhibit

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Terazosin hydrochloride
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HY-B0371F
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