TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is a gut-restricted, orally active agonist for G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 < 1 μM. TGR5 agonist 7 exhibits blood glucose lowering effect in mouse model, and can be used in diabete research.
For research use only. We do not sell to patients.
- Formula: C37H59N2NaO9S
- Molecular Weight:730.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 730.93
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Formula C37H59N2NaO9S
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SMILES
O=C([C@]1(CC[C@@]2([H])[C@](C)([H])COC(NCCS(=O)(O[Na])=O)=O)[C@@]2([H])[C@@]3([H])CC[C@]4([H])[C@@]5(C)CC[C@@H](OC(NC6CC6)=O)C(C)(C)[C@]5([H])CC[C@@]4(C)[C@]3(C)CC1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)