2. Anti-infection
  3. SARS-CoV
  4. TLP-3

TLP-3, Temporin L (HY-P2523) analogue, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 μM. TLP-3 inhibits protease activity through stabilizing hydrogen bonding and hydrophobic interactions with key enzyme residues. TLP-3 can be used for the research of ARS-CoV‑2 infection.

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TLP-3

TLP-3 Estructura química

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TLP-3 Related Antibodies

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Descripciòn

TLP-3, Temporin L (HY-P2523) analogue, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 μM. TLP-3 inhibits protease activity through stabilizing hydrogen bonding and hydrophobic interactions with key enzyme residues. TLP-3 can be used for the research of ARS-CoV‑2 infection[1].

In Vitro

TLP-3 stabilizes SARS-CoV-2 Mpro via favorable domain arrangement and forms strong hydrogen bond interactions with critical Mpro residues[1].
TLP-3 inhibits SARS-CoV-2 Mpro with an IC50 of 7.0 ± 1.5 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TLP-3 Related Antibodies
Peso molecular

1659.89

Fòrmula

C83H110N20O17
Sequence

Ser-Ala-Phe-Trp-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg
Sequence Shortening

SAFWQWFSKFLGR
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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TLP-3 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TLP-3TLP3TLP 3SARS-CoVSARS coronavirus3CLprocovid-19SARS-CoV-2 main proteaseTemporin LInhibitorinhibitorinhibit

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Nombre del producto:
TLP-3
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HY-P11579
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