TPE-GGH

TPE-GGH exhibits strong aggregation-induced emission property in DMSO/H₂O mixed solution^[1].
TPE-GGH (10 μM) exhibits a selective fluorescence "turn-off" response to Cu²⁺ in 10.0 mM HEPES solution, with strong anti-interference capability, and shows no significant fluorescence change in the presence of other tested metal ions^[1].
TPE-GGH (10 μM) binds to Cu²⁺ at a 1:1 stoichiometric ratio, with a binding constant of 7.9 × 10⁵ M^-1, and its limit of detection for Cu²⁺ in aqueous solution is 28.5 nM^[1].
TPE-GGH (10 μM) undergoes Cu²⁺-induced fluorescence quenching, a process mediated by a static quenching mechanism triggered by the paramagnetic heavy metal effect, which is associated with the dissociation of TPE-GGH aggregates and the coordination of Cu²⁺ with the amide and imidazole groups of TPE-GGH^[1].
TPE-GGH (10 μM; 9 min) exhibits reversible fluorescent response to Cu²⁺ within 7 cycles, and produces a rapid response to Cu²⁺ within 1 min^[1].
TPE-GGH (0-80 μM; 24 h) exhibits low cytotoxicity against LLC cells, with cell viability maintained above 90%^[1].
TPE-GGH (10 μM; 30 min) exhibits favorable cell membrane permeability in LLC cells, enabling the visualization of Cu²⁺ via gradual fluorescence quenching^[1].
TPE-GGH enables accurate detection of Cu²⁺ in pure water, tap water and lake water, with high recovery rates^[1].
Portable test strips prepared with TPE-GGH (10 μM; 30 min) enable visual qualitative detection of Cu²⁺ via distinct fluorescent color change under 365 nm UV light, and show no response to other tested metal ions^[1].
TPE-GGH (10 μM) combined with a smartphone RGB color recognition application enables semi-quantitative detection of Cu²⁺, with a linear G/B response and a limit of detection of 0.43 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.