TRITC-dextran, MW 70000
Based on 2 publication(s) in Google Scholar
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance.
For research use only. We do not sell to patients.
- Molecular Weight:70000.00
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) TRITC-dextran, MW 70000
More-
Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Biological Activity
Description
In Vitro
Paracellular Permeability Assay[1]
1. Add TRITC-dextran MW 70000 (20 mg/mL, 100 μL) to the basal medium in the upper chamber of a transwell (pore size 0.4 μm).
2. Collect the medium from the lower transwell chamber at 0, 30, 60, and 120 minutes.
3. Measure the fluorescence signal (Ex=544 nm, Em=570 nm).
4. Calculate the concentration of TRITC-dextran MW 70000 based on the fluorescence intensity.
5. Calculate the permeability rate.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Appearance Solid
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Molecular Weight 70000.00
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Color Purple to purplish red
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SMILES
[TRITC-dextran, MW 70000]
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Synonyms
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle-Mediated Angiogenesis and the NF-κB-PCLAF Signaling Axis. [Abstract]2025 Aug 18:e08613. PMID: 40820941
TRITC-dextran, MW 70000 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 18:e08613. [Abstract]
TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) in HUVEC monolayers treated with indicated sEVs. The permeability of HUVEC monolayers to TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) increased after exposure to CLTB‐NC‐sEVs and CLTB‐OE‐sEVs.
TRITC-dextran, MW 70000 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 18:e08613. [Abstract]
sEV-CLTB reduced TMR-dextran leakage. TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) permeability assay measuring vascular leakage in HUVECs. Fluorescence intensity in the lower chamber was quantified.
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J Vis Exp
Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice. [Abstract]2025 May 23:(219). PMID: 40489396
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (0.71 mM; Need ultrasonic)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)