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Cat. No.: HY-151611A

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UAMC-00050 free base

UAMC-00050 free base is a potent trypsin-like serine protease inhibitor. UAMC-00050 free base can be used in research of dry eye syndrome and ocular inflammation.

For research use only. We do not sell to patients.

CAS No.: 934622-26-1
Formula: C₃₃H₃₅N₆O₇P
Molecular Weight:658.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

UAMC-00050 free base Chemical Structure

CAS No.: 934622-26-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

UAMC-00050 free base is a potent trypsin-like serine protease inhibitor. UAMC-00050 free base can be used in research of dry eye syndrome and ocular inflammation^[1].

Chemical Information

CAS No. 934622-26-1
Molecular Weight 658.64
Formula C₃₃H₃₅N₆O₇P
SMILES

CC(NC1=CC=C(C=C1)OP(OC2=CC=C(C=C2)NC(C)=O)(C(NC(OCC3=CC=CC=C3)=O)CC4=CC=C(C=C4)NC(N)=N)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ceradini D, et, al. Improved synthesis of the selected serine protease uPA inhibitor UAMC-00050, a lead compound for the treatment of dry eye disease. 2022 Sep 30;26(10):2937-46.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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