UK4b
Based on 1 Customer Validation
UK4b is a highly selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. UK4b possesses anti-inflammatory and analgesic effects. UK4b can block the growth of abdominal aortic aneurysms in mice.
For research use only. We do not sell to patients.
- Purity: 96.17%
- CAS No.: 2171000-87-4
- Formula: C21H25ClN2O4
- Molecular Weight:404.89
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2171000-87-4
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Appearance Solid
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Molecular Weight 404.89
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Formula C21H25ClN2O4
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Color Off-white to yellow
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SMILES
ClC(C=C(/C=C1C(NC(NC/1=O)=O)=O)C=C2)=C2OCCCCC3CCCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (123.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4698 mL | 12.3490 mL | 24.6981 mL | 61.7452 mL |
| 5 mM | 0.4940 mL | 2.4698 mL | 4.9396 mL | 12.3490 mL | |
| 10 mM | 0.2470 mL | 1.2349 mL | 2.4698 mL | 6.1745 mL | |
| 15 mM | 0.1647 mL | 0.8233 mL | 1.6465 mL | 4.1163 mL | |
| 20 mM | 0.1235 mL | 0.6175 mL | 1.2349 mL | 3.0873 mL | |
| 25 mM | 0.0988 mL | 0.4940 mL | 0.9879 mL | 2.4698 mL | |
| 30 mM | 0.0823 mL | 0.4116 mL | 0.8233 mL | 2.0582 mL | |
| 40 mM | 0.0617 mL | 0.3087 mL | 0.6175 mL | 1.5436 mL | |
| 50 mM | 0.0494 mL | 0.2470 mL | 0.4940 mL | 1.2349 mL | |
| 60 mM | 0.0412 mL | 0.2058 mL | 0.4116 mL | 1.0291 mL | |
| 80 mM | 0.0309 mL | 0.1544 mL | 0.3087 mL | 0.7718 mL | |
| 100 mM | 0.0247 mL | 0.1235 mL | 0.2470 mL | 0.6175 mL |