2. Others GPCR/G Protein Neuronal Signaling
  3. Isotope-Labeled Compounds 5-HT Receptor Adrenergic Receptor
  4. Urapidil-d3

Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.

Para uso exclusivo en investigación. No vendemos a pacientes.

Urapidil-d<sub>3</sub>

Urapidil-d3 Estructura química

No. CAS : 1398066-08-4

Tamaño Precio Stock Cantidad
1 mg En stock
5 mg   Obtener un presupuesto  
10 mg   Obtener un presupuesto  

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Based on 1 Customer Validation

Other Forms of Urapidil-d3:

Urapidil-d3 Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas 5-HT Receptor:

Ver todas las isoformas
5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

Ver todos los productos específicos de isoformas Adrenergic Receptor:

Ver todas las isoformas
α adrenergic receptor β adrenergic receptor

  • Actividad biológica

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  • Referencias

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Descripciòn

Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

IC50 & Target

5-HT1A Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Urapidil-d3 Related Antibodies
Peso molecular

390.49

Fòrmula

C20H26D3N5O3
No. CAS
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])OC1=C(N2CCN(CC2)CCCNC(N(C(N3C)=O)C)=CC3=O)C=CC=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 25 mg/mL (64.02 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5609 mL 12.8044 mL 25.6089 mL
5 mM 0.5122 mL 2.5609 mL 5.1218 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5609 mL 12.8044 mL 25.6089 mL 64.0221 mL
5 mM 0.5122 mL 2.5609 mL 5.1218 mL 12.8044 mL
10 mM 0.2561 mL 1.2804 mL 2.5609 mL 6.4022 mL
15 mM 0.1707 mL 0.8536 mL 1.7073 mL 4.2681 mL
20 mM 0.1280 mL 0.6402 mL 1.2804 mL 3.2011 mL
25 mM 0.1024 mL 0.5122 mL 1.0244 mL 2.5609 mL
30 mM 0.0854 mL 0.4268 mL 0.8536 mL 2.1341 mL
40 mM 0.0640 mL 0.3201 mL 0.6402 mL 1.6006 mL
50 mM 0.0512 mL 0.2561 mL 0.5122 mL 1.2804 mL
60 mM 0.0427 mL 0.2134 mL 0.4268 mL 1.0670 mL
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Urapidil-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Urapidil-d31398066-08-4Isotope-Labeled Compounds5-HT ReceptorAdrenergic ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorBeta ReceptorInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Urapidil-d3
Cat. No.:
HY-B0716S1
Cantidad:
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