WYFA-15
Based on 1 Customer Validation
WYFA-15 is a sphingomyelin synthase 1 (SMS1) inhibitor that protects mice against lethal SFTSV infection and reduce SARS-CoV-2 replication and pathogenesis. WYFA-15 can be utilized in anti-virus research.
For research use only. We do not sell to patients.
- Purity: 98.77%
- Formula: C22H16Cl2N2O
- Molecular Weight:395.28
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 395.28
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Formula C22H16Cl2N2O
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Color Light yellow to brown
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SMILES
ClC1=CC=CC(Cl)=C1COC2=CC=CC=C2NC3=C4C=NC=CC4=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 70 mg/mL (177.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5299 mL | 12.6493 mL | 25.2985 mL | 63.2463 mL |
| 5 mM | 0.5060 mL | 2.5299 mL | 5.0597 mL | 12.6493 mL | |
| 10 mM | 0.2530 mL | 1.2649 mL | 2.5299 mL | 6.3246 mL | |
| 15 mM | 0.1687 mL | 0.8433 mL | 1.6866 mL | 4.2164 mL | |
| 20 mM | 0.1265 mL | 0.6325 mL | 1.2649 mL | 3.1623 mL | |
| 25 mM | 0.1012 mL | 0.5060 mL | 1.0119 mL | 2.5299 mL | |
| 30 mM | 0.0843 mL | 0.4216 mL | 0.8433 mL | 2.1082 mL | |
| 40 mM | 0.0632 mL | 0.3162 mL | 0.6325 mL | 1.5812 mL | |
| 50 mM | 0.0506 mL | 0.2530 mL | 0.5060 mL | 1.2649 mL | |
| 60 mM | 0.0422 mL | 0.2108 mL | 0.4216 mL | 1.0541 mL | |
| 80 mM | 0.0316 mL | 0.1581 mL | 0.3162 mL | 0.7906 mL | |
| 100 mM | 0.0253 mL | 0.1265 mL | 0.2530 mL | 0.6325 mL |