1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
    PAI-1
  3. ZK824190 hydrochloride

ZK824190 hydrochloride 

Cat. No.: HY-126361A
Handling Instructions

ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.

For research use only. We do not sell to patients.

ZK824190 hydrochloride Chemical Structure

ZK824190 hydrochloride Chemical Structure

CAS No. : 2629177-12-2

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5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 670 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2150 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3250 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively[1].

In Vivo

ZK824190 (2 mg/kg; PO; Rats with EAE model) exhibits a relatively high oral availability and a moderate half time (T1/2=2.8 h)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

450.86

Formula

C22H21ClF2N2O4

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Product Name:
ZK824190 hydrochloride
Cat. No.:
HY-126361A
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