Zolmitriptan N-Oxide-d6
Zolmitriptan N-Oxide-d6 is a deuterium labeled Zolmitriptan N-Oxide. Zolmitriptan N-Oxide is the major metabolite of Zolmitriptan. Zolmitriptan is a 5-HT1B/1D receptor partial agonist.
For research use only. We do not sell to patients.
- CAS No.: 1217618-32-0
- Formula: C16H15D6N3O3
- Molecular Weight:309.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217618-32-0
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Unlabeled Cas 251451-30-6
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Molecular Weight 309.39
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Formula C16H15D6N3O3
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SMILES
[2H]C([2H])([2H])[N+](C([2H])([2H])[2H])([O-])CCC(C1=C2)=CNC1=CC=C2C[C@H]3COC(N3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. E M Clement, et al. Simultaneous measurement of zolmitriptan and its major metabolites N-desmethylzolmitriptan and zolmitriptan N-oxide in human plasma by high-performance liquid chromatography with coulometric detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Jan 25;766(2):339-43. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)