1. Metabolic Enzyme/Protease
  2. Glucosidase
  3. α-Glucosidase-IN-22

α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research.

For research use only. We do not sell to patients.

α-Glucosidase-IN-22 Chemical Structure

α-Glucosidase-IN-22 Chemical Structure

CAS No. : 2870693-28-8

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5 mg USD 270 In-stock
10 mg USD 430 In-stock
25 mg USD 900 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research[1].

Molecular Weight

285.32

Formula

C14H11N3O2S

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (438.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5048 mL 17.5242 mL 35.0484 mL
5 mM 0.7010 mL 3.5048 mL 7.0097 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5048 mL 17.5242 mL 35.0484 mL 87.6209 mL
5 mM 0.7010 mL 3.5048 mL 7.0097 mL 17.5242 mL
10 mM 0.3505 mL 1.7524 mL 3.5048 mL 8.7621 mL
15 mM 0.2337 mL 1.1683 mL 2.3366 mL 5.8414 mL
20 mM 0.1752 mL 0.8762 mL 1.7524 mL 4.3810 mL
25 mM 0.1402 mL 0.7010 mL 1.4019 mL 3.5048 mL
30 mM 0.1168 mL 0.5841 mL 1.1683 mL 2.9207 mL
40 mM 0.0876 mL 0.4381 mL 0.8762 mL 2.1905 mL
50 mM 0.0701 mL 0.3505 mL 0.7010 mL 1.7524 mL
60 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.4603 mL
80 mM 0.0438 mL 0.2191 mL 0.4381 mL 1.0953 mL
100 mM 0.0350 mL 0.1752 mL 0.3505 mL 0.8762 mL
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α-Glucosidase-IN-22 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
α-Glucosidase-IN-22
Cat. No.:
HY-152158
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