1,2-Dierucoyl-sn-glycero-3-phosphocholine  (Synonyms: DEPC; L-Dierucoyl lecithin; Dierucoyllecithin)

1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity^[1][2].

Glucose oxidase (GO) is encapsulated in phosphatidylcholine vesicles (PC liposomes) for controlling the oxidation rate of glucose at 40°C. The GO in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) liposome shows the highest activity. In an external loop airlift bubble column, the oxidation reaction in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome system is markedly accelerated because of gas-liquid flow-induced membrane permeabilization to glucose^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

898.33

C₅₂H₁₀₀NO₈P

51779-95-4

Solid

White to off-white

CCCCCCCC/C=C\CCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC/C=C\CCCCCCCC

Room temperature in continental US; may vary elsewhere.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Masahiro INOUE, et al. Oxidation of Glucose in Gas-Liquid Flow Catalyzed by Glucose Oxidase-Containing Liposomes with Different Acyl Chain Properties. Journal of chemical engineering of japan. Published online, 2013.

  [2]. Weber ME, et al. Dynamic assessment of bilayer thickness by varying phospholipid and hydraphile synthetic channel chain lengths. J Am Chem Soc. 2005 Jan 19;127(2):636-42.  [Content Brief]