1,3-Dibromo-5,5-dimethylhydantoin
Based on 1 Customer Validation
1,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.20%
- CAS No.: 77-48-5
- Formula: C5H6Br2N2O2
- Molecular Weight:285.92
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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N-Chlorosuccinimide (Standard)
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Chloranil
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HY-Y0775
1-Bromo-2,5-pyrrolidinedione
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HY-Y0775R
1-Bromo-2,5-pyrrolidinedione (Standard)
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HY-Y0278R
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All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 77-48-5
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Appearance Solid
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Molecular Weight 285.92
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Formula C5H6Br2N2O2
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Color White to off-white
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SMILES
O=C1N(Br)C(C(C)(C)N1Br)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (349.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (944 KB)
- English - EN (944 KB)
- Français - FR (944 KB)
- Deutsch - DE (944 KB)
- Norwegian - NO (944 KB)
- Español - ES (944 KB)
- Swedish - SV (944 KB)
- Italian - IT (944 KB)
- Korean - KR (944 KB)
- Portuguese - PT (944 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4975 mL | 17.4874 mL | 34.9748 mL | 87.4370 mL |
| 5 mM | 0.6995 mL | 3.4975 mL | 6.9950 mL | 17.4874 mL | |
| 10 mM | 0.3497 mL | 1.7487 mL | 3.4975 mL | 8.7437 mL | |
| 15 mM | 0.2332 mL | 1.1658 mL | 2.3317 mL | 5.8291 mL | |
| 20 mM | 0.1749 mL | 0.8744 mL | 1.7487 mL | 4.3719 mL | |
| 25 mM | 0.1399 mL | 0.6995 mL | 1.3990 mL | 3.4975 mL | |
| 30 mM | 0.1166 mL | 0.5829 mL | 1.1658 mL | 2.9146 mL | |
| 40 mM | 0.0874 mL | 0.4372 mL | 0.8744 mL | 2.1859 mL | |
| 50 mM | 0.0699 mL | 0.3497 mL | 0.6995 mL | 1.7487 mL | |
| 60 mM | 0.0583 mL | 0.2915 mL | 0.5829 mL | 1.4573 mL | |
| 80 mM | 0.0437 mL | 0.2186 mL | 0.4372 mL | 1.0930 mL | |
| 100 mM | 0.0350 mL | 0.1749 mL | 0.3497 mL | 0.8744 mL |
1,3-Dibromo-5,5-dimethylhydantoin Related Classifications
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