DMPE-PEG1000 ammonium
Based on 1 Customer Validation
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a methoxy-capped PEGylated phospholipid containing two C14 lipid chains and a PEG1000 group. DMPE-PEG1000 can be incorporated as a PEG-lipid component into conjugated polymer nanoparticles for nanoparticle surface modification. DMPE-PEG1000 ammonium is applicable for researches related to PEGylated nanoparticle preparation and fluorescence imaging.
For research use only. We do not sell to patients.
- Purity : 99.91%
- CAS No.: 474922-82-2
- Formula: (C2H4O)nC35H68NO10P.NH3
- Molecular Weight:1000 (Average)
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
In Vitro
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is incorporated into PFBT conjugated polymer nanoparticles for PEGylated surface modification, and the resulting methoxy 1000 Mr PEG lipid-PFBT nanoparticles have a particle size of 26 nm as measured by TEM[1].
DMPE-PEG1000 ammonium serves as a methoxy PEG lipid component for the preparation of PEG lipid-CPN[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 474922-82-2
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Appearance Solid
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Molecular Weight 1000 (Average)
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Formula (C2H4O)nC35H68NO10P.NH3
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SMILES
O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCC)=O)=O)OCCOC.N.[n]
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Synonyms
14:0 PEG1000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Protocols
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Bioluminescent/Fluorescent Imaging Xenograft
Bioluminescent and fluorescent imaging xenograft models use tumor cells engineered to express optical reporters so tumor engraftment, growth, dissemination, and treatment response can be monitored longitudinally in living animals and validated ex vivo. Bioluminescence imaging usually measures luciferase activity after substrate administration and is commonly used as a surrogate for viable reporter-expressing tumor burden, while fluorescence imaging measures reporter or probe emission and can support tumor localization, ex vivo confirmation, or complementary multimodal analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- DMPE-PEG1000
- 474922-82-2
- 14:0 PEG1000 PE
- 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000]
- Liposome
- J774A.1 mouse macrophage cells
- quantum yield
- biocompatibility
- conjugated polymer nanoparticles
- CD16/32 receptors
- aqueous solution stability
- cell surface receptors
- streptavidin
- magnetic beads
- glass surfaces
- Inhibitor
- inhibitor
- inhibit