17β-HSD5 inhibitor 1
17β-HSD5 inhibitor 1 (Compound 29) is a potent 17β-HSD5 inhibitor, with an IC50 of 2.9 nM in HEK-293 cells overexpressing human 17β-HSD5.
For research use only. We do not sell to patients.
- CAS No.: 243638-37-1
- Formula: C24H32O2
- Molecular Weight:352.51
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All 17β-HSD Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
2.9 nM
Compound: 26
|
Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone after 18 hrs
Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone after 18 hrs
|
[PMID: 18472187] |
Chemical Information
-
CAS No. 243638-37-1
-
Molecular Weight 352.51
-
Formula C24H32O2
-
SMILES
C[C@@]12[C@]3(CC[C@@]1([H])[C@@]4([H])[C@](C5=CC=CC=C5CC4)([H])CC2)OC(C(C)(CC3)C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz