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  3. Biochemical Assay Reagents
  4. 18:0 DAP

18:0 DAP is a cationic or ionizable lipid with no unsaturated bonds in its hydrocarbon chain. The mRNA encapsulation efficiency of 18:0 DAP is 0%. 18:0 DAP cannot form functional lipid nanoparticles suitable for mRNA delivery.

For research use only. We do not sell to patients.

18:0 DAP

18:0 DAP Chemical Structure

CAS No. : 121315-93-3

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18:0 DAP Related Antibodies

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Description

18:0 DAP is a cationic or ionizable lipid with no unsaturated bonds in its hydrocarbon chain. The mRNA encapsulation efficiency of 18:0 DAP is 0%. 18:0 DAP cannot form functional lipid nanoparticles suitable for mRNA delivery[1].

In Vitro

18:0 DAP (50 molar ratio; immediately after preparation) fails to form functional LNPs with mRNA, as evidenced by 0% encapsulation efficiency, a large hydrodynamic size, and a high PDI[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

18:0 DAP Related Antibodies
Molecular Weight

652.09

Formula

C41H81NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(CC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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18:0 DAP Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

18:0 DAP121315-93-3Biochemical Assay Reagentslipid nanoparticlesLNPssubretinal injectionhydrocarbon chainsretinal mRNA deliverycationic lipidionizable lipidmRNAInhibitorinhibitorinhibit

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