2-Heptyl-4-quinolone
Based on 1 Customer Validation
2-Heptyl-4-quinolone is an intermediate in the synthesis of the Pseudomonas quinolone signal (PQS) that controls swarming by positively regulating phenazine production. 2-Heptyl-4-quinolone induces the production of the phenazine-1-carboxylic acid (PCA).
For research use only. We do not sell to patients.
- Purity: 99.06%
- CAS No.: 40522-46-1
- Formula: C16H21NO
- Molecular Weight:243.34
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
35 μM
Compound: 1
|
Antiproliferative activity against human A2780 cells after 2 days by Alamar blue assay
Antiproliferative activity against human A2780 cells after 2 days by Alamar blue assay
|
[PMID: 28648491] |
Chemical Information
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CAS No. 40522-46-1
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Appearance Solid
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Molecular Weight 243.34
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Formula C16H21NO
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Color Light yellow to yellow
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SMILES
O=C1C=C(CCCCCCC)NC2=C1C=CC=C2
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Structure Classification
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Initial Source
Pseudomonas aeruginosa
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 50 mg/mL (205.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1095 mL | 20.5474 mL | 41.0948 mL | 102.7369 mL |
| 5 mM | 0.8219 mL | 4.1095 mL | 8.2190 mL | 20.5474 mL | |
| 10 mM | 0.4109 mL | 2.0547 mL | 4.1095 mL | 10.2737 mL | |
| 15 mM | 0.2740 mL | 1.3698 mL | 2.7397 mL | 6.8491 mL | |
| 20 mM | 0.2055 mL | 1.0274 mL | 2.0547 mL | 5.1368 mL | |
| 25 mM | 0.1644 mL | 0.8219 mL | 1.6438 mL | 4.1095 mL | |
| 30 mM | 0.1370 mL | 0.6849 mL | 1.3698 mL | 3.4246 mL | |
| 40 mM | 0.1027 mL | 0.5137 mL | 1.0274 mL | 2.5684 mL | |
| 50 mM | 0.0822 mL | 0.4109 mL | 0.8219 mL | 2.0547 mL | |
| 60 mM | 0.0685 mL | 0.3425 mL | 0.6849 mL | 1.7123 mL | |
| 80 mM | 0.0514 mL | 0.2568 mL | 0.5137 mL | 1.2842 mL | |
| 100 mM | 0.0411 mL | 0.2055 mL | 0.4109 mL | 1.0274 mL |