2-(p-Tolyl)propanoic acid
Based on 1 Customer Validation
2-(p-Tolyl) propanoic acid (2-(4-methylphenyl) propionic acid) acts as an Antimicrobial agent intermediate. 2-(p-Tolyl) propanoic acid inhibits COX-1 and COX-2 enzymes, with IC50 values of 38.23 μM and 64.30 μM, respectively. 2-(p-Tolyl) propanoic acid is applicable to research on E. coli, Enterococcus faecalis, Listeria monocytogenes, and Staphylococcus aureus.
For research use only. We do not sell to patients.
- CAS No.: 938-94-3
- Formula: C10H12O2
- Molecular Weight:164.20
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
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COX-1 38.23 μM (IC50) |
COX-2 64.30 μM (IC50) |
2-(p-Tolyl) propanoic acid inhibits COX-1 and COX-2 enzymes with IC50 values of 38.23 μM and 64.30 μM, respectively[1].
2-(p-Tolyl) propanoic acid exhibits a MIC of 25 μg/mL against Escherichia coli (ATCC 35218)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 938-94-3
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Appearance Solid-Liquid Mixture
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Molecular Weight 164.20
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Formula C10H12O2
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SMILES
O=C(O)C(C1=CC=C(C=C1)C)C
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Synonyms
2-(4-Methylphenyl)propionic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- 2-(p-Tolyl)propanoic acid
- 938-94-3
- 2-(4-Methylphenyl)propionic acid
- COX
- Bacterial
- Drug Intermediate
- COX-1
- Klebsiella pneumoniae NCTC 9633
- E. coli (ATCC 35218)
- Listeria monocytogenes ATCC 1911
- Escherichia coli ATCC 35218
- Escherichia coli ATCC 25922
- COX-2
- Enterococcus faecalis ATCC 29212
- cyclooxygenase inhibitor
- Staphylococcus aureus ATCC 25923
- Inhibitor
- inhibitor
- inhibit