244cis
Based on 1 Customer Validation
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels.
For research use only. We do not sell to patients.
- Purity : 99.67%
- CAS No.: 2956402-64-3
- Formula: C60H111N3O6
- Molecular Weight:970.54
-
Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
-
HY-W598178
93-O17OCationic Lipid -
HY-145405
C12-200Cationic Lipidoid -
HY-153186
LNP Lipid-3Ionizable Lipid -
HY-153378
Lipid 15Ionizable Lipid -
HY-147332
TCL053Nucleic Acid Carrier -
HY-160439
Ionizable lipid-2Cationic Lipid -
HY-156630
Ionizable lipid-1Ionizable Lipid -
HY-153377
Lipid 14Amino Lipid -
HY-160553
9322-O16BIonizable Cationic Lipid -
HY-149156
Lipid C24Lipid -
HY-157252
CL4F8-6Cationic Lipid -
HY-159716
Lipid 50Ionizable Lipid
Biological Activity
Description
Chemical Information
-
CAS No. 2956402-64-3
-
Appearance Liquid
-
Molecular Weight 970.54
-
Formula C60H111N3O6
-
Color Colorless to light yellow
-
SMILES
CCCCCC/C=C\COC(CCCCCCCCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCN1CCN(CC1)CCCCCCCCC(OC/C=C\CCCCCC)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Solution, -20°C, 2 years
Solvent & Solubility
In Vitro:
Ethanol : 50 mg/mL (51.52 mM; Need ultrasonic)
Protocols
-
RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
Purity & Documentation
-
Data Sheet (265 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.0304 mL | 5.1518 mL | 10.3035 mL | 25.7589 mL |
| 5 mM | 0.2061 mL | 1.0304 mL | 2.0607 mL | 5.1518 mL | |
| 10 mM | 0.1030 mL | 0.5152 mL | 1.0304 mL | 2.5759 mL | |
| 15 mM | 0.0687 mL | 0.3435 mL | 0.6869 mL | 1.7173 mL | |
| 20 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL | 1.2879 mL | |
| 25 mM | 0.0412 mL | 0.2061 mL | 0.4121 mL | 1.0304 mL | |
| 30 mM | 0.0343 mL | 0.1717 mL | 0.3435 mL | 0.8586 mL | |
| 40 mM | 0.0258 mL | 0.1288 mL | 0.2576 mL | 0.6440 mL | |
| 50 mM | 0.0206 mL | 0.1030 mL | 0.2061 mL | 0.5152 mL |
244cis Related Classifications
HY-160552 Related Classifications
Powered by Bioz