2956402-64-3

244cis Chemical Structure
2956402-64-3

Chemical Structure

244cis

  • CAS No.: 2956402-64-3
  • Formula:C60H111N3O6
  • Molecular Weight:970.54

InChIKey: LLTJKESWTCPZGG-IHTYGJSSSA-N

SMILES: CCCCCC/C=C\COC(CCCCCCCCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCN1CCN(CC1)CCCCCCCCC(OC/C=C\CCCCCC)=O)=O

Biological Activity: 244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels[1].
The product specifications provided below refer solely to the active content of 244cis.

Cat. No. Product Name Purity Description Pricing
HY-160552 		244cis 99.67% 244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels.
The product specifications provided below refer solely to the active content of 244cis.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

Keywords