3-Bromopyruvic acid (Standard)
3-Bromopyruvic acid (Standard) is the analytical standard of 3-Bromopyruvic acid (HY-19992). This product is intended for research and analytical applications. 3-Bromopyruvate (Bromopyruvic acid) is an analogue of pyruvate and a potent hexoKinase (HK)-II inhibitor with high tumor selectivity. 3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis. 3-Bromopyruvate induces autophagy by stimulating ROS formation in breast cancer cells. Antimicrobial activities.
For research use only. We do not sell to patients.
- CAS No.: 1113-59-3
- Formula: C3H3BrO3
- Molecular Weight:166.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1113-59-3
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Molecular Weight 166.96
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Formula C3H3BrO3
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SMILES
O=C(O)C(CBr)=O
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Synonyms
Bromopyruvic acid (Standard); 3-BrPA (Standard); HexoKinase II Inhibitor II, 3-BP (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gan L, et al. Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy. Onco Targets Ther. 2020;13:11125-11137. Published 2020 Oct 29. [Content Brief]
[2]. Chen Y, et al. 3 Bromopyruvate sensitizes human breast cancer cells to TRAIL induced apoptosis via the phosphorylated AMPK mediated upregulation of DR5. Oncol Rep. 2018;40(5):2435-2444. [Content Brief]
[3]. Zhang Q, et al. Hexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cells. Genes Cancer. 2014;5(3-4):100-112. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Bromopyruvic acid (Standard) Related Classifications
HY-19992R Related Classifications
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