2. 4-Butyl-alpha-agarofuran

4-Butyl-alpha-agarofuran  (Synonyms: Buagafuran; Buagarofuran)

Cat. No.: HY-19496
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4-Butyl-alpha-agarofuran (AF 5) is an anxiolytic and antidepressant agent. 4-Butyl-alpha-agarofuran a α-agarofuran derivative that can be isolated from Gharu-wood. 4-Butyl-alpha-agarofuran can be used for the research of neurological disease research.

For research use only. We do not sell to patients.

4-Butyl-alpha-agarofuran Chemical Structure

4-Butyl-alpha-agarofuran Chemical Structure

CAS No. : 272126-07-5

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4-Butyl-alpha-agarofuran Related Antibodies

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Description

4-Butyl-alpha-agarofuran (AF 5) is an anxiolytic and antidepressant agent. 4-Butyl-alpha-agarofuran a α-agarofuran derivative that can be isolated from Gharu-wood. 4-Butyl-alpha-agarofuran can be used for the research of neurological disease research[1].

In Vitro

4-Butyl-alpha-agarofuran (2 mg) is completely metabolized in 100 min to the hydroxy derivative I and carbonyl derivative II in human liver microsome incubation system[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Butyl-alpha-agarofuran Related Antibodies
In Vivo

4-Butyl-alpha-agarofuran (0.5-10 mg/kg; i.p., once) shows antianxiety effects in a social interaction test and the serotonin (5-HT) levels of striatum, cortex, and midbrain are significantly decreased[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats[1]
Dosage: 0.5, 1.0, 2.0, 4.0, 5.0 and 10.0 mg/kg
Administration: Intraperitoneal injection; 0.5, 1.0, 2.0, 4.0, 5.0 and 10.0 mg/kg; once
Result: Dose-dependently prolonged the total time spent in social interaction test at a dose range of 0.5-2.0 mg/kg. Decreased the 5-HT levels in brain tissues, decreased dopamine levels of in rat striatum and midbrain and also reduced the cortical level of epinephrine at a dose of 5 mg/kg after acute administration. Decresed the extracellular dopamine level in the striatum at a dose of 10 mg/kg.
Molecular Weight

262.43

Formula

C18H30O
CAS No.
SMILES

C[C@]12CC[C@@](C3)([H])C(C)(C)O[C@@]13C(CCCC)=CCC2
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Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Butyl-alpha-agarofuran272126-07-5Buagafuran BuagarofuranInhibitorinhibitorinhibit

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