4'-Demethylpodophyllotoxone
4'-Demethylpodophyllotoxone is an intermediate product of the biotransformation of Alternaria alternata S-f6. After 4'-Demethylpodophyllotoxone is modified with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP), the resulting novel compound can strongly inhibit the growth of human gastric cancer cell line (BGC-823).
For research use only. We do not sell to patients.
- CAS No.: 93780-84-8
- Formula: C21H18O8
- Molecular Weight:398.36
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H9 | EC50 |
0.8 μM
Compound: 16
|
Evaluation for anti-HIV activity using T cell line (H9).
Evaluation for anti-HIV activity using T cell line (H9).
|
10.1016/S0960-894X(97)10108-1 |
| H9 | IC50 |
1.7 μM
Compound: 16
|
Cytotoxicity against H9 cell line
Cytotoxicity against H9 cell line
|
10.1016/S0960-894X(97)10108-1 |
Chemical Information
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CAS No. 93780-84-8
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Appearance Solid
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Molecular Weight 398.36
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Formula C21H18O8
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Color White to off-white
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SMILES
O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)O)C4=CC(OCO5)=C5C=C4C([C@@]2([H])CO1)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)