4-Fluorobenzeneboronic acid-d4
4-Fluorobenzeneboronic acid-d4 (P-Fluorophenylboronic acid-d4) is the deuterated-labeled 4-Fluorobenzeneboronic acid (HY-I0201). 4-Fluorobenzeneboronic acid (P-Fluorophenylboronic acid) is a fluorinated arylboronic acid coupling ligand and precursor. Under the catalysis of heterogeneous palladium nanoparticles, 4-Fluorobenzeneboronic acid participates in the Suzuki-Miyaura C-C coupling reaction to generate fluorinated biphenyl derivatives. 4-Fluorobenzeneboronic acid also participates in the copper-catalyzed three-component reaction with nitrobenzene and potassium metabisulfite as substrates, and finally produces sulfonamides through the formation of arylsulfinate intermediates, copper-assisted S-N bond construction and reduction steps.
For research use only. We do not sell to patients.
- CAS No.: 1254771-90-8
- Formula: C6H2D4BFO2
- Molecular Weight:143.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1254771-90-8
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Unlabeled CAS 1765-93-1
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Molecular Weight 143.94
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Formula C6H2D4BFO2
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SMILES
[2H]C1=C(B(O)O)C([2H])=C([2H])C(F)=C1[2H]
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Synonyms
P-Fluorophenylboronic acid-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Fluorobenzeneboronic acid-d4 Related Classifications
HY-I0201S Related Classifications
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Keywords
- 4-Fluorobenzeneboronic acid-d4
- 1254771-90-8
- P-Fluorophenylboronic acid-d4
- Isotope-Labeled Compounds
- Biochemical Assay Reagents
- nitrobenzene
- fluorinated aryl bromides
- sulfonamides
- arylsulfinate
- copper-catalyzed three-component reactions
- potassium metabisulfite
- Pd nanoparticle
- G-COOH-Pd-10
- 1-bromo-4-fluorobenzene
- Suzuki-Miyaura C-C coupling reactions
- Inhibitor
- inhibitor
- inhibit