2. PROTAC
  3. Ligands for E3 Ligase
  4. 6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole

6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole is an E3 ligase ligand used in the synthesis of the PROTAC Androgen receptor degrader-1 (HY-175652).

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6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole

6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole Chemical Structure

CAS No. : 2766178-76-9

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6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41

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Description

6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole is an E3 ligase ligand used in the synthesis of the PROTAC Androgen receptor degrader-1 (HY-175652)[1].

IC50 & Target

Cereblon

 

Masse moléculaire

243.26

Formule

C13H13N3O2
CAS No.
SMILES

CN1C=CC2=CC=C(N3C(NC(CC3)=O)=O)C=C12
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole2766178-76-9Ligands for E3 LigaseE3 ligase-recruiting MoietyAndrogen receptorROTACInhibitorinhibitorinhibit

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Nom du produit:
6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole
Cat. No.:
HY-175654
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