98N12-5
Based on 1 publication(s) in Google Scholar
98N12-5 is a lipid delivery material that assembles to form lipid nanoparticles and mediates the intracellular delivery of siRNA to hepatocytes. 98N12-5 is used in RNA interference-related research.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 917572-74-8
- Formula: C81H163N9O5
- Molecular Weight:1343.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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306Oi10Ionizable Lipidoid -
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Lipid 29Lipid -
HY-148859
AA-T3A-C12AA-Lipidoid
Publications Citing Use of MedChemExpress (MCE) 98N12-5
More
Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 917572-74-8
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Appearance Solid
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Molecular Weight 1343.22
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Formula C81H163N9O5
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Color Off-white to light yellow
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SMILES
CCCCCCCCCCCCNC(CCN(CCN(CCC(NCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCC)=O)CCNCCN(CCC(NCCCCCCCCCCCC)=O)CCC(NCCCCCCCCCCCC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
2026 Mar 24:e17931. PMID: 41875360
Solvent & Solubility
In Vitro:
THF : 50 mg/mL (37.22 mM; Need ultrasonic)
DMSO : 50 mg/mL (37.22 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 50 mg/mL (37.22 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| THF / DMSO / Ethanol | 1 mM | 0.7445 mL | 3.7224 mL | 7.4448 mL | 18.6120 mL |
| 5 mM | 0.1489 mL | 0.7445 mL | 1.4890 mL | 3.7224 mL | |
| 10 mM | 0.0744 mL | 0.3722 mL | 0.7445 mL | 1.8612 mL | |
| 15 mM | 0.0496 mL | 0.2482 mL | 0.4963 mL | 1.2408 mL | |
| 20 mM | 0.0372 mL | 0.1861 mL | 0.3722 mL | 0.9306 mL | |
| 25 mM | 0.0298 mL | 0.1489 mL | 0.2978 mL | 0.7445 mL | |
| 30 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.6204 mL |
98N12-5 Related Classifications
HY-112772A Related Classifications
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