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Acetoacetic acid sodium salt 

Cat. No.: HY-112540B Purity: >98.0%
Handling Instructions

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes.

For research use only. We do not sell to patients.

Acetoacetic acid sodium salt Chemical Structure

Acetoacetic acid sodium salt Chemical Structure

CAS No. : 623-58-5

Size Price Stock Quantity
10 mM * 1 mL in Water USD 132 In-stock
Estimated Time of Arrival: December 31
5 mg USD 120 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].

In Vitro

Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].
Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes[1].

Molecular Weight

124.07

Formula

C₄H₅NaO₃

CAS No.

623-58-5

SMILES

CC(CC(O[Na])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (403.00 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.0600 mL 40.2998 mL 80.5997 mL
5 mM 1.6120 mL 8.0600 mL 16.1199 mL
10 mM 0.8060 mL 4.0300 mL 8.0600 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Acetoacetic acid sodium salt
Cat. No.:
HY-112540B
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