1. GPCR/G Protein
  2. Neuropeptide Y Receptor

Neuropeptide Y (13-36), amide, human (Synonyms: Neuropeptide Y (13-36), human)

Cat. No.: HY-P1480
Handling Instructions

Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Neuropeptide Y (13-36), amide, human Chemical Structure

Neuropeptide Y (13-36), amide, human Chemical Structure

CAS No. : 122341-40-6

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References


Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.

IC50 & Target

Neuropeptide Y receptor[1]

In Vivo

Intraventricular injections of the Y2 neuropeptide Y receptor agonist porcine Neuropeptide Y (13-36) (25-3000 pM) produces a dose-dependent increase (up to 14%; ED50=0.3 nM for overall effects and 0.97 nM for the peak effects) in mean arterial blood pressure in the awake, unrestrains male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].

Animal Administration


Neuropeptide Y (13-36) dissolved in 30 μL mock cerebrospinal fluid (CSF), or CSF alone, is injected (30/μL/3 min) by means of an automatic micro-injection pump into the lateral ventricle of freely moving, unrestrained male rats. Five doses of Neuropeptide Y (13-36) (25, 75, 750, 1250, 3000 pM) are injected in order to evaluate possible dose-dependent effects and the effects are compared with the CSF group. A threshold dose of Neuropeptide Y (13-36) is also injected together with a dose of Neuropeptide Y (1-36) (75 pM), close to the ED50 value for its overall vasodepressor action in awake rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight








Sequence Shortening



Please store the product under the recommended conditions in the Certificate of Analysis.


Room temperature in continental US; may vary elsewhere

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Neuropeptide Y (13-36), amide, human
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Neuropeptide Y (13-36), amide, human

Cat. No.: HY-P1480