2. Cell Cycle/DNA Damage
  3. Cyclin G-associated Kinase (GAK)
  4. Nigakinone

Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.

For research use only. We do not sell to patients.

Nigakinone Chemical Structure

Nigakinone Chemical Structure

CAS No. : 18110-86-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 469 In-stock
Solution
10 mM * 1 mL in DMSO USD 469 In-stock
Solid
1 mg USD 160 In-stock
5 mg USD 400 In-stock
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Based on 1 publication(s) in Google Scholar

Nigakinone Related Antibodies

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Description

Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.

Molecular Weight

266.25

Formula

C15H10N2O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C(OC)=C1O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (31.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7559 mL 18.7793 mL 37.5587 mL
5 mM 0.7512 mL 3.7559 mL 7.5117 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7559 mL 18.7793 mL 37.5587 mL 93.8967 mL
5 mM 0.7512 mL 3.7559 mL 7.5117 mL 18.7793 mL
10 mM 0.3756 mL 1.8779 mL 3.7559 mL 9.3897 mL
15 mM 0.2504 mL 1.2520 mL 2.5039 mL 6.2598 mL
20 mM 0.1878 mL 0.9390 mL 1.8779 mL 4.6948 mL
25 mM 0.1502 mL 0.7512 mL 1.5023 mL 3.7559 mL
30 mM 0.1252 mL 0.6260 mL 1.2520 mL 3.1299 mL
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Nigakinone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nigakinone18110-86-6Cyclin G-associated Kinase (GAK)Auxilin 2Inhibitorinhibitorinhibit

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