2. Infection

Infection (感染症)

Infection

関連製品

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-N12617
    Bipolaricin R 98%
    Bipolaricin R (Compound 6) is a compound that can be isolated from Bipolaris maydis. Bipolaricin R exhibits noticeable antimicrobial ability against Bacillus cereus, Staphylococcus aureus, and Staphylococcus epidermidis. Bipolaricin R has excellent antiproliferation and apoptosis induction effects against A549 cell line.
    Bipolaricin R
  • HY-N12637
    Kagimminol B 98%
    Kagimminol B, a cembrene-type diterpenoid, can be isolated from an Okeania sp. marine cyanobacterium. Kagimminol B shows selective growth-inhibitory activity against the causative agent of human African trypanosomiasis.
    Kagimminol B
  • HY-N12647
    cis-Hinkiresinol 230292-85-0 98%
    cis-Hinkiresinol is a bioactive constituent of Rhizoma anemarrhenae. Rhizoma anemarrhenae is reprted to have anti-pathogenic microorganism, hypoglycemic effects, anti-inflammatory, antipyretic effects and anti-platelet aggregation.
    cis-Hinkiresinol
  • HY-N12660
    Quorum sensing-IN-4 98%
    Quorum sensing-IN-4 (compound 2) is a quorum sensing inhibitor, and can be isolated from Thailand mangrove-derived Streptomyces strain, OUCMDZ-5511.
    Quorum sensing-IN-4
  • HY-N12682
    Phoslactomycin C 159991-59-0 98%
    Phoslactomycin C has weak effect against Gram-positive bacteria, but has strong effect against fungi.
    Phoslactomycin C
  • HY-N12686
    Dichamanetin 58779-09-2
    Dichamanetin, a C-benzylated flavanone that can be isolated from Piper sarmentosum, is a potent antibacterial and anticancer agent. Dichamanetin displays antibacterial activity against a panel of Gram-positive strains, including resistant S. aureus strains with MIC values in the range of 1-7.5 μg/mL. Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components via mitochondrial-mediated apoptosis. Dichamanetin can be used for colon, prostate, breast cancer and infection research.
    Dichamanetin
  • HY-N12716
    Longipedunin A 886441-72-1 98%
    Longipedunin A is a HIV-1 Protease inhibitor with an IC50 value of 50 µg/mL.
    Longipedunin A
  • HY-N12723
    Talaroderxine D 98%
    Talaroderxine D (compound 4) has biofilm inhibitory effect. Talaroderxine D shows antimicrobial activities against Bacillus subtilis and Staphylococcus aureus with MIC values of 2.1 and 8.3 μg/mL.
    Talaroderxine D
  • HY-N12726
    Halociline 2977255-36-8 98%
    Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities.
    Halociline
  • HY-N12743
    Farobin A 1245447-08-8 98%
    Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α.
    Farobin A
  • HY-N12944
    18-Hydroxycamptothecin 116139-46-9 98%
    18-Hydroxycamptothecin is a camptothecin analogue that can be isolated from Camptotheca acuminata. Camptothecin compounds possess potential activities such as anti-cancer and anti-viral properties.
    18-Hydroxycamptothecin
  • HY-N13011
    Maniladiol 595-17-5
    Maniladiol is a triterpenoid that can be isolated from the flowers of Chrysanthemum morifolium. Maniladiol exhibits antitubercular activity against Mycobacterium tuberculosis strain H37Rv with a MIC of 4 mg/mL. Maniladiol can be used for Mycobacterium tuberculosis infection research.
    Maniladiol
  • HY-N13031
    Bellericagenin A 141630-18-4 98%
    Bellericagenin A is a pentacyclic triterpenic acid isolated from the bark of Terminalia bellerica. Bellericagenin A exhibits antimicrobial activity. Bellericagenin A exhibits a high affinity to alcohol dehydrogenase (ADH), which has the potential for ameliorating the alcoholic liver injury.
    Bellericagenin A
  • HY-N13141
    Tetracenomycin X 121245-07-6
    Tetracenomycin X is a natural aromatic polyketide compound. Tetracenomycin X can inhibit peptide bond formation between an incoming aminoacyl-tRNA and a terminal Gln-Lys (QK) motif in the nascent polypeptide. Tetracenomycin X can be used for the development of novel aromatic polyketide antibiotics .
    Tetracenomycin X
  • HY-N13154
    Malolactomycin C 189759-03-3 98%
    Malolactomycin C (compound 1) is a macrolide antifungal antibiotic isolated from Streptomyces strain KP-3144. Malolactomycin C is an effective inhibitor of Botrytis cinerea and thus controls a variety of plant diseases including gray mold.
    Malolactomycin C
  • HY-N13196
    Arcopilin A 98%
    Arcopilin A (compound Arcopilin A(1))is an antibacterial agent. Arcopilin A has weak inhibitory effects on fungal pathogens and Gram-positive bacteria, with IC50 values of 8.9 μg/mL and 14 μg/mL for cells KB-3-1 and L929, but it can effectively destroy preformed biofilms of Staphylococcus aureus. Arcopilin A can enhance the activities of gentamicin (GM; HY-K1050) and vancomycin (Vac; HY-B0671) by 115 and 31 times, respectively.
    Arcopilin A
  • HY-N13197
    6-Methyl-5,6-dihydro-2H-pyran-2-one 108-54-3 98%
    6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities.
    6-Methyl-5,6-dihydro-2H-pyran-2-one
  • HY-N13259
    Fluopsin C 31323-25-8 98%
    Fluopsin C is a copper-containing antibiotic with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity.
    Fluopsin C
  • HY-N13614
    Centaurein 35595-03-0 98%
    Centaurein, a flavonoid, is an IFN-γ promoter enhancer. Centaurein up-regulates the activity of NFAT and NF-κB enhancers. Centaurein increases the IFN-γ expression in T and NK cells and the serum IFN-γ level in mice. Centaureidin completely relaxes the contractions in intact rat aortic rings. Centaurein effectively protects mice against Listeria infection[1][2][3][4].
    Centaurein
  • HY-N13712
    Lucidenic lactone 250643-34-6 98%
    Lucidenic lactone is a terpene compound, is a DNA polymerase inhibitor. Lucidenic lactone inhibits calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase with IC50 values of 42 μM, 99 μM, and 69 μM, respectively.
    Lucidenic lactone
製品番号 製品名 / Synonyms Application Reactivity