1. Anti-infection Metabolic Enzyme/Protease
  2. Fungal Bacterial Endogenous Metabolite
  3. Anserinone B

Anserinone B is an antifungal and antibacterial benzoquinone. Anserinone B causes radial growth reductions of 50% and 37% against S.fimicola and A. furfuraceus, respectively. Anserinones B also displays moderate cytotoxicity in the NCI’s 60 human tumor cell line panel (GI50=4.4 µg/mL).

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Anserinone B

Anserinone B Chemical Structure

CAS No. : 190895-96-6

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Description

Anserinone B is an antifungal and antibacterial benzoquinone. Anserinone B causes radial growth reductions of 50% and 37% against S.fimicola and A. furfuraceus, respectively. Anserinones B also displays moderate cytotoxicity in the NCI’s 60 human tumor cell line panel (GI50=4.4 µg/mL)[1].

IC50 & Target[1]

Microbial Metabolite

 

Cellular Effect
Cell Line Type Value Description References
C6 IC50
< 10 μM
Compound: 8
Cytotoxicity against rat C6 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
Cytotoxicity against rat C6 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
[PMID: 34787427]
HGC-27 IC50
< 10 μM
Compound: 8
Cytotoxicity against human HGC-27 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
Cytotoxicity against human HGC-27 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
[PMID: 34787427]
SH-SY5Y IC50
< 10 μM
Compound: 8
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
[PMID: 34787427]
Molecular Weight

210.23

Formula

C11H14O4

CAS No.
SMILES

O=C(C=C1OC)C(C)=C(C[C@H](O)C)C1=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anserinone B
Cat. No.:
HY-N10307
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