Integrin Inhibitor
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UR-3216
0 ImagesCat. No.: HY-122230CAS No.: 220386-65-2UR-3216 is a selective, and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 has the potential for cardiovascular diseases research.
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Excisanin A
0 ImagesCat. No.: HY-136699CAS No.: 78536-37-5Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer.
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Anti-CD11b Antibody (ICRF44)
0 ImagesCat. No.: HY-P991836Anti-CD11b Antibody (ICRF44) reacts with the human CD11b. Anti-CD11b Antibody (ICRF44) recognizes the α subunit of the CD11b/CD18 complex, an α/β heterodimeric surface glycoprotein on human leukocytes. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
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Anti-CD103 Antibody (hCD103.01A)
0 ImagesCat. No.: HY-P992051Anti-CD103 Antibody (hCD103.01A) is a monoclonal antibody targeting human CD103 and can be used in cancer immunotherapy and immunological research. Recommend Isotype Controls: human IgG1 kappa, Isotype Control (HY-P99001).
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BI-1950
0 ImagesCat. No.: HY-124040CAS No.: 1159724-42-1BI-1950 is a lymphocyte function-associated antigen 1 (LFA-1) inhibitor. BI-1950 regulates immune system function through interaction with LFA-1. BI-1950 can be used in the research of inflammatory diseases.
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AFP464
0 ImagesCat. No.: HY-16031ACAS No.: 468719-53-1Synonyms: NSC710464AFP464 (NSC710464) is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 is applicable to research related to breast cancer.
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ATL 1102 sodium
0 ImagesCat. No.: HY-153481ASynonyms: ISIS-107248 sodium; Avicursen sodiumATL 1102 (Avicursen) sodium is a novel second-generation antisense oligonucleotide to CD49d mRNA
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Roxifiban
0 ImagesCat. No.: HY-10307CAS No.: 170902-47-3Roxifiban is a platelet glycoprotein (GP) IIb/IIIa receptor inhibitor that can be used in the study of angina.
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Anti-Fibulin-4 Antibody (5G11)
0 ImagesCat. No.: HY-P991850Anti-Fibulin-4 Antibody (5G11) reacts with the human fibulin-4. Anti-Fibulin-4 Antibody (5G11) does not show any crossreactivity with other family members. Fibulin-4 is an elastic-fibre-associated glycoprotein.
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Crocatin B
0 ImagesCat. No.: HY-N15519CAS No.: 143816-02-8Crocatin B is found in P. crocatum Ruiz & Pav. Crocatin B exerts anti-inflammatory activity by inhibiting the expression of TNF-α and ICAM-1. Crocatin B has anti-tumor activity.
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Anti-Mouse CD11b Antibody (5C6)
0 ImagesCat. No.: HY-P991773Anti-Mouse CD11b Antibody (5C6) is a CD11b blocking antibody. Anti-Mouse CD11b Antibody (5C6) can be used for in vitro inhibition of myelomonocytic cell adhesion and in vivo inhibition of inflammatory cell recruitment. Recommend Isotype Controls: Rat IgG2b kappa, Isotype Control (HY-P990682).
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GRGDSPK TFA
0 ImagesCat. No.: HY-P0322ASynonyms: EMD 56574 TFAGRGDSPK TFA (EMD 56574 TFA) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK TFA is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK TFA is used to study the role of integrins in bone formation and resorption.
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Gly-Arg-Gly-Asp-Ser TFA
0 ImagesCat. No.: HY-P0295ACAS No.: 2828433-23-2Synonyms: GRGDS TFAGly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM.
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GR83895
0 ImagesCat. No.: HY-P1702CAS No.: 152323-73-4GR83895 is a RGD based peptide, and inhibits ADP-induced platelet aggregation of human gel-filtered platelets (IC50= 0.9 μM).
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Anti-Integrin α9 Antibody
0 ImagesCat. No.: HY-P992049
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Eptifibatide monoacetate
0 ImagesCat. No.: HY-B0686ACAS No.: 1248559-53-6Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity.
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PDI-IN-4
0 ImagesCat. No.: HY-170655CAS No.: 3104129-77-0PDI-IN-4 is a highly selective inhibitor of human PDI (IC50=0.48 μM) with no significant cytotoxicity. PDI-IN-4 binds to PDI in a reversible manner, not only forming a covalent bond with the Cys400 residue but also engaging in hydrophobic interactions with other residues. By inhibiting the activation of GPIIb/IIIa, PDI-IN-4 effectively blocks platelet aggregation and thrombus formation. PDI-IN-4 can serve as an important tool reagent for thrombosis-related research.
