Nav1.7 Modulator
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PF-06526290
0 ImagesCat. No.: HY-126007PF-06526290 is a voltage-gated sodium (Nav) channel modulator with dual activity of enhancing and inhibiting Nav channel conduction. PF-06526290 slows inactivation by binding to the resting state of Nav channels, and exerts inactivation state-dependent inhibition after prolonged depolarization by acting on the voltage sensor of the fourth homologous domain 4 (D4 VSD). PF-06526290 can be used in research on neurological disorders such as epilepsy and autism.
