1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14733
    31-Homorifamycin W
    31-Homorifamycin W is an antibiotic found in Amycolatopsis mediterranei.
    31-Homorifamycin W
  • HY-A0166R
    Cilastatin (Standard)
    Cilastatin (Standard) is the analytical standard of Cilastatin. This product is intended for research and analytical applications. Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin is an antibacterial adjunct.
    Cilastatin (Standard)
  • HY-B2072AR
    Cephaloridine hydrate (Standard)
    Cefadroxil (hydrate) (Standard) is the analytical standard of Cefadroxil (hydrate). This product is intended for research and analytical applications. Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2.
    Cephaloridine hydrate (Standard)
  • HY-123436
    Sarubicin B
    Sarubicin B is an active product that can be isolated from the culture filtrate of a Streptomyces strain JA 2861. Sarubicin B is a quinone antibiotic that inhibit Gram-positive bacteria and not active against Gram-negative microorganisms.
    Sarubicin B
  • HY-129312
    Awamycin
    Awamycin is an antitumor ansamycin antibiotic.
    Awamycin
  • HY-N14291
    4-Methoxy-p-toluquinone
    4-Methoxy-p-toluquinone is a quinone antibiotic found in the fungus Coprinus siniilis, Lentinus degener. 4-Methoxy-p-toluquinone has anti-bacterial, mycobacterial and fungal effects, but is weak against Gram-negative bacteria. The serum will inactivate it.
    4-Methoxy-p-toluquinone
  • HY-N14387
    5-Hydroxy-9-methylstreptimidone
    5-Hydroxy-9-methylstreptimidone is a glutarimide antibiotic. 5-Hydroxy-9-methylstreptimidone has a weak weeding effect.
    5-Hydroxy-9-methylstreptimidone
  • HY-N6686R
    Virginiamycin M1 (Standard)
    Virginiamycin M1 (Standard) is the analytical standard of Virginiamycin M1. This product is intended for research and analytical applications. Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by?Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665). Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.
    Virginiamycin M1 (Standard)
  • HY-N15092
    Milbemycin α11
    Milbemycin α11 (Meilingmycin A) is an antibiotic and has the effect of killing nematodes and mites.
    Milbemycin α11
  • HY-N14595
    Resorcinomycin B
    Resorcinomycin B is an antibiotic found in Streptoverticillum roseoverticillatum.
    Resorcinomycin B
  • HY-A0071R
    Tildipirosin (Standard)
    Tildipirosin (Standard) is the analytical standard of Tildipirosin. This product is intended for research and analytical applications. Tildipirosin, a long-acting macrolide, has antibiotic activity.
    Tildipirosin (Standard)
  • HY-N14281
    Himalomycin B
    Himalomycin B is an anthraquinone antibiotic. Himalomycin B has strong activity against Staphylococcus aureus, Escherichia coli and Streptomyces vuridochromogenes.
    Himalomycin B
  • HY-N13880
    Adustin
    Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM.
    Adustin
  • HY-N14210
    Epithienamycin F
    Epithienamycin F is a carbapenem antibiotic. Epithienamycin F has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity.
    Epithienamycin F
  • HY-N14745
    Elaiomycin
    Elaiomycin has activity against Gram-positive bacteria, some anaerobic bacteria, Eimeria tenella, E.acervulina.
    Elaiomycin
  • HY-N14705
    2-Hydroxygentamicin C2
    2-Hydroxygentamicin C2 is an antibiotic of the gentamicin group with anti-Gram-positive and negative bacteria activity.
    2-Hydroxygentamicin C2
  • HY-W741555
    Dechlorogriseofulvin
    Dechlorogriseofulvin (7-Dechlorogriseofulvin) is an antibiotic, and exhibits inhibitory activity against various plant pathogenic fungi. Dechlorogriseofulvin inhibits Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum with MIC of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively.
    Dechlorogriseofulvin
  • HY-B0398S
    Nalidixic Acid-d5
    Nalidixic Acid-d5 is the deuterium labeled Nalidixic acid. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria.
    Nalidixic Acid-d<sub>5</sub>
  • HY-N14322
    Mollisin
    Mollisin is a quinone antibiotic with antifungal activity.
    Mollisin
  • HY-P1674
    Murepavadin
    Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance.
    Murepavadin

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