2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W741555
    Dechlorogriseofulvin
    Dechlorogriseofulvin (7-Dechlorogriseofulvin) is an antibiotic, and exhibits inhibitory activity against various plant pathogenic fungi. Dechlorogriseofulvin inhibits Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum with MIC of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively.
    Dechlorogriseofulvin
  • HY-B0398S
    Nalidixic Acid-d5
    Nalidixic Acid-d5 is the deuterium labeled Nalidixic acid. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria.
    Nalidixic Acid-d<sub>5</sub>
  • HY-N14322
    Mollisin
    Mollisin is a quinone antibiotic with antifungal activity.
    Mollisin
  • HY-P1674
    Murepavadin
    Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance.
    Murepavadin
  • HY-N14173
    Epiderstatin
    Epiderstatin is a glutarimide antibiotic. Epiderstatin has the activity of inhibiting the filamentous division induced by epidermal growth factor (EGF), but does not inhibit EGF-receptor kinase. Epiderstatin has only weak antifungal activity and no antibacterial effect.
    Epiderstatin
  • HY-B1275R
    Cephalothin sodium (Standard)
    Cephalothin (Cephalotin) sodium (Standard) is the analytical standard of Cephalothin sodium (HY-B1275). This product is intended for research and analytical applications. Cephalothin sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies.
    Cephalothin sodium (Standard)
  • HY-N8339
    Decatromicin B
    Decatromicin B is an antibiotic. Decatromicin B has potent antibacterial activities against both Gram-positive and Gram-negative bacteria. Decatromicin B can be isolated from Actimonadura sp..
    Decatromicin B
  • HY-N14274
    Miyakamide A1
    Miyakamide A1 is an antibiotic with insecticidal effect. Miyakamide A1 inhibits the growth of Artemia salina. Miyakamide A1 has a weak antixanthomonas activity. Miyakamide A1 inhibits P388 cells with an IC50 of 10.5 μg/mL.
    Miyakamide A1
  • HY-N14456
    Platenomycin A0
    Platenomycin A0 is a macrolide antibiotic with anti-Gram-positive bacteria activities.
    Platenomycin A0
  • HY-125395
    Altromycin G
    Altromycin G is an antibiotic that primarily targets Gram-positive bacteria and has strong antitumor activity.
    Altromycin G
  • HY-130471
    Sannamycin C
    Sannamycin C is an aminoglycoside antibiotic. Sannamycin C has weak antibacterial activity against Gram-positive bacteria.
    Sannamycin C
  • HY-121148
    Mutalomycin
    Mutalomycin is a polyether antibiotic. Mutalomycin has anti-Gram-positive bacteria, anti-mycoplasma and anti-coccidial activity.
    Mutalomycin
  • HY-N14888
    Phyllosinol
    Phyllosinol is an antifungal antibiotic.
    Phyllosinol
  • HY-N12223
    Piericidin B
    Piericidin B (compound 8) is an antibiotic that provides strong antibacterial defense for wasp larvae.
    Piericidin B
  • HY-W780199
    Endophenazine B
    Endophenazine B is a phenazine antibiotic, and it has low herbicidal activity against Lemna minor.
    Endophenazine B
  • HY-N7066R
    Difloxacin hydrochloride (Standard)
    Difloxacin (hydrochloride) (Standard) is the analytical standard of Difloxacin (hydrochloride). This product is intended for research and analytical applications. Difloxacin hydrochloride is a broad-spectrum antibacterial agent. Difloxacin hydrochloride inhibits bacterial DNA gyrase and exhibits a concentration-dependant bactericidal effect by interference with the activity of DNA gyrase and topoisomerase IV.
    Difloxacin hydrochloride (Standard)
  • HY-176337
    4'-Acetyl-chrysomycin A
    4'-Acetyl-chrysomycin A is an analog of chrysomycin A. 4'-Acetyl-chrysomycin A has antibacterial activity.
    4'-Acetyl-chrysomycin A
  • HY-N14718
    Porothramycin A
    Porothramycin A is an antibiotic. Porothramycin A has activity against Gram-positive bacteria and anaerobic bacteria.
    Porothramycin A
  • HY-N15080
    S-2,3-Dicarboxyaziridine
    		Inhibitor
    S-2,3-Dicarboxyaziridine, a metabolite that can be isolated from a streptomyces, possesses anti-bacterial activity.
    S-2,3-Dicarboxyaziridine
  • HY-N15114
    Polymyxin A1
    Polymyxin A1 is a heteropeptide antibiotic found in different strains of Bacillus polymyxa, and its effect against Gram-negative bacteria is greater than that against Gram-positive bacteria.
    Polymyxin A1
Antibiotic Isoform Comparison

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