2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P3252AS
    Pegcetacoplan-13C3,15N TFA
    Pegcetacoplan-13C3,15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
    Pegcetacoplan-<sup>13</sup>C<sub>3</sub>,<sub>15</sub>N TFA
  • HY-112167S
    GDC-0575-d4
    GDC-0575-d4 (ARRY-575-d4) is the deuterium labeled GDC-0575 (HY-112167). GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.
    GDC-0575-d<sub>4</sub>
  • HY-W768044
    3-(1-Nitrosopyrrolidin-2-yl)pyridine-13C6
    3-(1-Nitrosopyrrolidin-2-yl)pyridine-13C6 is the 13C-labeled 3-(1-Nitrosopyrrolidin-2-yl)pyridine (HY-W189682). 3-(1-Nitrosopyrrolidin-2-yl)pyridine is a major tobacco-specific nitrosamine.
    3-(1-Nitrosopyrrolidin-2-yl)pyridine-<sup>13</sup>C<sub>6</sub>
  • HY-W837593
    (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid-15N
    (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid-15N is the 15N-labeled (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid (HY-W013182). (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid is an aspartic acid derivative.
    (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid-<sup>15</sup>N
  • HY-145539SA
    1,2-Dipalmitoyl-sn-glycero-3-PS-d62 ammonium
    1,2-Dipalmitoyl-sn-glycero-3-PS-d62 ammonium is the deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-PS ammonium. 1,2-Dipalmitoyl-sn-glycero-3-PS is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS is used for the preparation of phospholipid bilayers.
    1,2-Dipalmitoyl-sn-glycero-3-PS-d<sub>62</sub> ammonium
  • HY-30216AS
    Leucic acid-13C
    Leucic acid-13C (α-Hydroxyisocaproic acid-13C) is the 13C-labeled Leucic acid (HY-30216A). Leucic acid is an amino acid metabolite.
    Leucic acid-<sup>13</sup>C
  • HY-42487S1
    Exatecan Intermediate 1-d2
    Exatecan Intermediate 1-d2 is the deuterium labeled Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects.
    Exatecan Intermediate 1-d<sub>2</sub>
  • HY-111451S
    Tuvusertib-d3
    Tuvusertib-d3 (M1774-d3) is the deuterium labeled Tuvusertib (HY-111451). Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor with a Ki value below 1 μΜ.
    Tuvusertib-d<sub>3</sub>
  • HY-135035S1
    Decanoyl-L-carnitine-d19
    Decanoyl-L-carnitine-d19 ((-)-Decanoylcarnitine-d19> is the deuterium labeled Decanoyl-L-carnitine (HY-135035). Decanoyl-L-carnitine ((-)-Decanoylcarnitine) is an endogenous metabolite. Decanoyl-L-carnitine can be used as a serum metabolic biomarkers as indicators in the progression of intravenous leiomyomatosis.
    Decanoyl-L-carnitine-d<sub>19</sub>
  • HY-109506S10
    DPPC-13C
    DPPC-13C3 (129Y83-13C) is the 13C-labeled DPPC (HY-109506). DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
    DPPC-<sup>13</sup>C
  • HY-W002300S1
    Boc-L-Valine-15N
    Boc-L-Valine-15N is the 15N-labeled Boc-L-Valine (HY-W002300). Boc-L-Valine is a valine derivative.
    Boc-L-Valine-<sup>15</sup>N
  • HY-B0627S1
    Metformin-13C2 (hydrochloride)
    Metformin-13C2 (1,1-Dimethylbiguanide-13C2) hydrochloride is the 13C-labeled Metformin hydrochloride (HY-17471A). Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, Metformin hydrochloride regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo.
    Metformin-<sup>13</sup>C<sub>2</sub> (hydrochloride)
  • HY-159846S
    Luvometinib-d
    Luvometinib-d is the deuterium labeled Luvometinib (HY-159846). Luvometinib is a mitogen-activated protein kinase (MEK) inhibitor with antitumor activity.
    Luvometinib-d
  • HY-17571S
    Oxytocin-13C6,15N TFA
    Oxytocin-13C6,15N (α-Hypophamine-13C6,15N) TFA is the 13C- and 15N-labeled Oxytocin TFA. Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma.
    Oxytocin-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N TFA
  • HY-W753763
    Sucrose-13C12
    Sucrose-13C12 (D-(+)-Saccharose-13C12) is the 13C-labeled Sucrose (HY-B1779). Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al.
    Sucrose-<sup>13</sup>C<sub>12</sub>
  • HY-13562S
    Banoxantrone-d12
    Banoxantrone-d12 is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
    Banoxantrone-d<sub>12</sub>