VAV1 Inhibitor
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6-Thio-GTP tetrasodium
0 ImagesCat. No.: HY-131598CPurity: 99.7%Synonyms: 6-Thioguanosine-5'-triphosphate tetrasodium6-Thio-GTP (tetrasodium) is a Vav1-Rac inhibitor. 6-Thio-GTP (tetrasodium) inhibits TCR-stimulated T cell proliferation and CD28-mediated T cell survival. 6-Thio-GTP (tetrasodium) has an immunosuppressive effect in a mouse cardiac allograft transplant model and prolongs cardiac allograft survival.
The product specifications provided below refer solely to the active content of 6-Thio-GTP tetrasodium.
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AB19
0 ImagesCat. No.: HY-179119AB19 is a potent Vav1 inhibitor. AB19 inhibits Vav1 and reduces its downstream ERK phosphorylation. AB19 shows anti-proliferative activity in pancreatic cancer models. AB19 can be used for pancreatic cancer research.
