A-348441
A-348441 is a liver selective glucocorticoid receptor antagonist. A-348441 can reduce the glucose level in the liver. A-348441 can be used for the research of metabolic disease, such as type 2 diabetes.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 639520-46-0
- 화학식: C54H75NO7
- 분자량:850.18
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
10 nM
Compound: 2
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Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assay
Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assay
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[PMID: 16987661] |
Chemical Information
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CAS No. 639520-46-0
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분자량 850.18
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화학식 C54H75NO7
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SMILES
C[C@@]12[C@](CC[C@@]2(O)C#CC)([H])[C@@]3([H])C([C@@H](C4=CC=C(N(C)CCO[C@@H]5C[C@]6([H])[C@@](C)([C@]7([H])[C@@]([C@@]8([H])[C@@](C)([C@]([C@H](C)CCC(O)=O)([H])CC8)[C@@H](O)C7)([H])[C@H](O)C6)CC5)C=C4)C1)=C9C(CC3)=CC(CC9)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-348441 Related Classifications
HY-108061 Related Classifications
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